Percorrer por autor "Teixeira, Rita"
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- Análise multielementar e quimiometria na autenticidade de alimentos: Pera RochaPublication . Coelho, Inês; Matos, Ana; Teixeira, Rita; Nascimento, Ana; Bordado, João; Donard, Olivier; Castanheira, IsabelA combinação da análise multielementar com a técnicas de quimiometria utilizadas permitiu agrupar as amostras de acordo com a sua região de origem, contribuindo para a sua autenticidade assim como para um maior conhecimento da sua composição nutricional.
- Characteristics and incidence trends of adults hospitalized with community-acquired pneumonia in Portugal, pre-pandemicPublication . Carneiro, Joana; Teixeira, Rita; Leite, Andreia; Lahuerta, Maria; Catusse, Julie; Ali, Mohammad; Lopes, SílviaCommunity-acquired pneumonia (CAP) is a major cause of hospitalization that leads to substantial morbidity, mortality, and costs. Evaluating CAP trends over time is important to understand patterns and the impact of public health interventions. This study aims to describe the characteristics and trends in the incidence of adults hospitalized with CAP in Portugal between 2010 and 2018. In this study, we included hospitalization data, prevalence of comorbidities, and population data. CAP hospitalizations of adults (≥18y) living in mainland Portugal discharged from public hospitals were identified using ICD-9-CM or ICD-10-CM codes. Based on previous CAP studies, we selected nine relevant comorbidities. We described the frequency and incidence of CAP hospitalizations per sex, age group, comorbidity, and year of discharge. Trends were explored using Joinpoint regression. We observed 470,545 CAP hospitalizations falling into the 2010-18 period. The majority were males (54.8%) and aged ≥75 years (65.3%). Most often recorded comorbidities were congestive heart failure (26.4%), diabetes (25.5%), and chronic pulmonary disease (19.2%). The Joinpoint regression identified a gradual decline in the incidence rates of CAP hospitalizations for both sexes and all age groups. Of the nine comorbidities selected, seven showed a progressive increase in incidence rates followed by a subsequent decline (all except HIV/AIDS and chronic renal disease). Our findings offer valuable insights for selecting priority groups for public health interventions and design strategies to mitigate the burden of CAP.
- Combining multielement analysis and chemometrics to trace the geographical origin of Rocha pearPublication . Coelho, Inês; Matos, Ana Sofia; Teixeira, Rita; Nascimento, Ana; Bordado, João; Donard, Olivier; Castanheira, IsabelThis work aims at characterizing the mineral profile of a Portuguese variety of pear, Rocha pear, and study the relationship between the nutritional profile and geographical origin. Multielement analysis of twenty-four elements (Al, As, B, Be, Ca, Cd, Co, Cr, Cu, Fe, K, Li, Mg, Mn, Mo, Na, Ni, P, Pb, Se, Sn, Sr, Tl, Zn) was performed using an ICP-MS and ICP-OES, on 50 samples originating from two regions, one with Protected Designation of Origin (PDO), known as “Pera Rocha do Oeste”, and the other without (nPDO). Correlation analysis was performed to check for potential relationships between elements. Results from PDO and nPDO regions were compared using chemometric tools, namely Principal Component Analysis, Hierarquical Cluster Analysis and Linear Discriminant Analysis (LDA). The predictive model, built and validated, classified samples according to their regional origin with 100% accuracy. The present study shows that multielement analysis combined with the appropriate statistical tools can be a valuable contribution from the identification of the geographical provenance of Rocha Pears. It provides important nutritional information regarding the mineral composition of Rocha pears, not available until know, promoting the linkage between the nutritional profile and geographical origin, filling the gap of absent values in FCDBs.
- Development of a digestion method to assist multi-element determination in Rocha pear by ICP-MSPublication . Castanheira, Isabel; Coelho, Inês; Teixeira, Rita; Ventura, MartaThe Rocha pear is a Portuguese variety of pear (Pyrus communis L.), harvested in August but available for consumption practically all year round, due to the refrigeration process. The West region of Portugal is classified as Protected Designation of Origin (PDO). This variety is responsible for 95% of the national pear production and represents an important economic activity with exportations over 67 million Euros per year. In the present work a method for pear digestion, prior to analysis by ICP-MS, has been developed and optimized. The elements analyzed were Cr, Mn, Co, Ni, Cu, As, Se, Sr, Mo, Cd, Sn and Pb. After the removal of seeds pear samples were freeze-dried and vacuum sealed until analysis. A graphite heating block (digiprep) was used for sample digestion. For method development different combinations of sample weight; high purity nitric acid; high purity hydrogen peroxide and digestion conditions were compared. The results showed that weighing more than 0.7g of sample leads to an incomplete digestion evidenced by the presence of solid residues in the digestion tube. The same was noticeable in samples that had not been soaked in nitric acid overnight. In all analyzed samples Se, Sn and Pb were below the limit of quantification. This work concludes that the most suitable digestion method for freeze dried pears is obtained by adding 8ml of ultrapure HNO3 to 0.7g of sample. Samples are left in acid overnight and digested in a heating block for 130 min at 95°C on the next day.
- Risk of stroke or myocardial infarction hospitalisation following hospitalisation for community-acquired pneumonia in Portugal: a self-controlled case series studyPublication . Carneiro, Joana; Leite, Andreia; Lahuerta, Maria; Catusse, Julie; Ali, Mohammad; Teixeira, Rita; Lopes, SílviaObjectives: We aimed to assess the risk of cardiovascular hospitalisations (stroke or myocardial infarction (MI)) following a community-acquired pneumonia (CAP) hospitalisation in a large Portuguese administrative dataset. Design: Self-controlled case series study. Setting: We used hospitalisation data from National Health Service hospitals across Portugal between 2010 and 2018. Participants: Adults hospitalised for both CAP and stroke/MI in Portugal during the 2010-2018 period (n=13 494, of which 10 400 with stroke and 3094 with MI). Primary and secondary outcome measures: We considered CAP hospitalisation as the exposure (14-, 28- and 91-day exposure periods) and acute cardiovascular (stroke or MI) hospitalisations as the outcome. Incidence rate ratios (IRR) were computed using a conditional Poisson regression (overall and by sex and age subgroups). Results: Patients were mostly male and above 75 years. Stroke/MI hospitalisation incidence was higher following CAP, compared with the baseline period. Largest differences were observed in the 14-day period after discharge (IRR for stroke: 2.55, 95% CI: 2.33-2.80; IRR for MI: 3.23, 2.78-3.75), compared with the 28-day (IRR for stroke: 2.06, 1.92-2.22; IRR for MI: 2.62, 2.32-2.95) and 91-day periods (IRR for stroke: 1.37, 1.30-1.44; IRR for MI: 1.75, 1.60-1.91). A similar trend was observed for sex and age subgroups. Conclusions: Our study shows an increased risk of stroke/MI for CAP patients, particularly during the first 2 weeks after being discharged. Effective postdischarge monitoring and follow-up, combined with efforts to prevent CAP occurrence, could improve patient outcomes.
- ´Rocha’ pear antioxidant and mineral characterizationPublication . Coelho, Inês; Rego, Andreia; Teixeira, Rita; Nascimento, Ana; Bordado, João; Santos, Rui; Castanheira, IsabelIntroduction: ‘Rocha’ pear (Pyrus communis L.) is a Portuguese native variety with a Protected Designation of Origin (PDO). This variety is responsible for 95% of the national pear production and represents an important economic activity1 with exportations over 67 million Euros per year2. Pears are very nutritive fruits, rich in micronutrients, antioxidants and other important nutrients. Its nutritional value has been widely studied. However, in comparison to other European pears like Bartllet and Red Anjou, whose nutritional value is well known and published in reference databases, ‘Rocha’ pear’s nutritional quality has been less studied. Objectives and methodology: The objective of this study was to evaluate an antioxidant and mineral characterization of ‘Rocha’ pear. Antioxidant capacity was characterized by testing the elimination of free radicals DPPH (2,2-diphenyl-1-picrylhydrazyl) and by the Folin-Ciocalteau method. Minerals and trace elements were quantified by ICP-MS and ICP-OES after a graphite heating block (digiprep) digestion. Elements analyzed were Cr, Mn, Co, Cu, Se, Sr, Mo, Sn, Zn, Fe, Mg, P, K, Ca and Na. ‘Rocha’ pear samples were collected from 11 farms in 2 Portuguese regions (Fundão and PDO region). Each laboratory sample was a pool of three pears. One sample was used to study differences between peel and pulp. After the removal of seeds pear samples were freeze-dried and vacuum sealed until analysis. Main findings: The PDO pears have the highest antioxidant capacity, presenting a phenolic content ranging from 0,65 to 0,84 mg eq. Galic acid/ g sample and an IC50 from 0,26 to 0,17 mg/ml. As expected the majority of compounds with antioxidant proprieties are in the peel, with proximally two times more than the pulp. In terms of micronutrients no significant differences were found between the regions under study. The exception is zinc and sodium that presents higher values for the PDO region. Conclusions: In conclusion, it is important to study and to divulge the Portuguese pear in a higher extension, once it will lead to a higher consumption by the population and consequently to a national economic growth.
- Tracing the geographical origin of food products with multielement fingerprinting and chemometrics: the case of Rocha pearPublication . Coelho, Inês; Matos, Ana S.; Teixeira, Rita; Nascimento, Ana; Bordado, João; Donard, Olivier; Castanheira, IsabelThe present work aims to develop a chemical fingerprint of Rocha pears produced within the PDO region based on multielement analysis.