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Publication
Medi_COR: estudo do perfil farmacoterapĂȘutico da coorte e_COR
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Advisor(s)
Abstract(s)
O estudo Medi_COR analisou o padrĂŁo de consumo de medicamentos e sua relação com os fatores de risco cardiovascular na população portuguesa. Este estudo envolveu 1688 adultos com idades compreendidas entre os 18 e 79 anos, provenientes das vĂĄrias regiĂ”es de Portugal continental (coorte e_COR). Observou-se um elevado consumo de medicamentos nesta população; foram identificadas 409 substĂąncias ativas e associaçÔes e 73% dos participantes referiram tomar pelo menos um medicamento, com destaque para os anti-hipertensores (21%) e os agentes antidislipidĂ©micos (11%). Foi tambĂ©m observada uma alta prevalĂȘncia de polimedicação (27%). O maior consumo de medicamentos ocorreu entre os 61-70 anos, com diferenças por gĂ©nero: mulheres consumem mais antidepressivos e ansiolĂticos, enquanto homens utilizam mais antidiabĂ©ticos orais e insulinas, especialmente a partir da quarta dĂ©cada de vida. O grupo farmacoterapĂȘutico mais consumido foi o cardiovascular, refletindo a elevada prevalĂȘncia de doenças cardiovasculares, concordante com o estudo e_COR. A anĂĄlise tambĂ©m revelou baixa utilização de medicamentos para cessação tabĂĄgica e emagrecimento, apesar da alta prevalĂȘncia de tabagismo e obesidade na população.
Os resultados reforçam a necessidade de intervençÔes mais direcionadas para melhorar o controlo das doenças crónicas e otimizar o uso dos medicamentos.
O estudo destaca a importĂąncia de uma gestĂŁo terapĂȘutica cuidadosa, especialmente dos polimedicados, para minimizar riscos e maximizar a eficĂĄcia dos tratamentos.
The Medi_COR study analyzed the pattern of medication use and its relationship with cardiovascular risk factors in the Portuguese population. This study included 1688 adults aged 18 to 79 years from various regions of mainland Portugal (e_COR cohort). A high consumption of medications was observed in this population; 409 active substances and combinations were identified, and 73% of partiicipants reported taking at least one medication, with a notable prevalence of antihypetensives (21%) and lipid- lowering agents (11%). A high prevalence of polypharmacy (27%) was also observed. The highest consumption of medications occurred among individuals aged 61-70 years, with gender di fferences: women consumed more antidepressants and anxiolytics, while men used more oral antidiabetics and insulin,especially from the fourth decade of life onward. The most consumed pharmacotherapeutic group was cardiovascular drugs, reflecting the high prevalence of cardiovascular diseases, consistent with findings from the e_COR study. The analysis also revealed low use of medications for smoking cessation and weight loss, despite the high prevalence of smoking and obesity in the population. The results underscore the need for more targeted interventions to improve the management of chronic diseases and optimize medication use. The study highlights the importance of careful therapeutic management, especially among individuals with polypharmacy, to minimize risks and maximize treatment efficacy.
The Medi_COR study analyzed the pattern of medication use and its relationship with cardiovascular risk factors in the Portuguese population. This study included 1688 adults aged 18 to 79 years from various regions of mainland Portugal (e_COR cohort). A high consumption of medications was observed in this population; 409 active substances and combinations were identified, and 73% of partiicipants reported taking at least one medication, with a notable prevalence of antihypetensives (21%) and lipid- lowering agents (11%). A high prevalence of polypharmacy (27%) was also observed. The highest consumption of medications occurred among individuals aged 61-70 years, with gender di fferences: women consumed more antidepressants and anxiolytics, while men used more oral antidiabetics and insulin,especially from the fourth decade of life onward. The most consumed pharmacotherapeutic group was cardiovascular drugs, reflecting the high prevalence of cardiovascular diseases, consistent with findings from the e_COR study. The analysis also revealed low use of medications for smoking cessation and weight loss, despite the high prevalence of smoking and obesity in the population. The results underscore the need for more targeted interventions to improve the management of chronic diseases and optimize medication use. The study highlights the importance of careful therapeutic management, especially among individuals with polypharmacy, to minimize risks and maximize treatment efficacy.
Description
Keywords
Doenças Cardio e CĂ©rebro-vasculares Avaliação do Risco Determinantes da SaĂșde e da Doença Consumo de Medicamentos Perfil FarmacoterapĂȘutico Medi_COR Portugal
Pedagogical Context
Citation
Boletim Epidemiológico ObservaçÔes. 2025 maio-agosto;14(38): 58-65
Publisher
Instituto Nacional de SaĂșde Doutor Ricardo Jorge, IP