Browsing by Author "Alves de Matos, A.P."
Now showing 1 - 2 of 2
Results Per Page
Sort Options
- Electron-microscopy characterization of cells infected with a new phlebovirus isolated in sandflies from south PortugalPublication . Amaro, Fátima; Zé-Zé, Líbia; Alves, M.J.; Alves de Matos, A.P.Phlebovirus genus is comprised by arthropod-borne viruses and is one of the five genera that compose Bunyaviridae family [1]. Viruses within this family mature intracellularly and their RNA replicates in the cytoplasm, while the viral proteins transit through the Endoplasmic Reticulum and Golgi apparatus [2]. Serological studies in human Portuguese populations have proven that Toscana virus, a neurotropic phlebovirus, is present in Portugal but there were no data about phleboviral activity in arthropod vectors [3]. In this context, and in order to detect sandflies naturally infected by phleboviruses, an entomological surveillance was conducted in Arrabida region, in the south of Portugal.
- Ultrastructural and immunofluorescence studies of Zika infectionPublication . Alves de Matos, A.P.; Zé-Zé, Líbia; Amaro, Fátima; Alves, Maria JoãoZika virus is a flavivirus transmitted by mosquitoes from the Aedes genus, sexually, or by vertical transmission. It was discovered in 1947 in Africa and it is thought to produce, in some cases, microcephaly in newborns and the Guilan–Barre syndrome in adults. The otherwise low pathogenicity of the virus for humans precluded its detailed study. Recently, outbreaks in Pacific islands, with a virus related to Asian strains, were followed by a large outbreak in Brazil, which easily spread to all Latin-American countries and Cape Verde in África. Ultrastructural information on Zika’s effects on cells is very limited. Also an early histopathological study signaled alterations on other organs, which have not been further explored. (...)