| dc.contributor.author | Manageiro, Vera | |
| dc.contributor.author | Ferreira, Eugénia | |
| dc.contributor.author | Louro, Deolinda | |
| dc.contributor.author | The Antimicrobial Resistance Surveillance Program in Portugal | |
| dc.contributor.author | Caniça, Manuela | |
| dc.date.accessioned | 2017-02-15T13:47:40Z | |
| dc.date.available | 2017-02-15T13:47:40Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | All 6 KPC-3-producing Enterobacteriaceae isolates (5 K. pneumoniae and 1 Enterobacter cloacae), identified among 61 isolates, from different Portuguese health institutions (March 2010 to December 2011) were multidrug resistant, showing susceptibility only to colistin. The blaKPC-3 gene, conferring resistance to carbapenemes, was present alone or in combination with other bla genes: blaSHV-26, blaCTX-M-15, and the ESBL blaSHV-164, here firstly described. The Tn4401-harbouring blaKPC-3 encountered in all isolates, showed a 68 bp deletion upstream of the bla gene. All but two KPC-3-containing plasmids revealed the following types: IncFrepB plus IncFIIs (n=3) and IncFrepB plus IncP (n=1). Dissemination of blaKPC seems to be due to carriage of similar KPC-harbouring plasmids within genetically distinct K. pneumoniae (ST14, ST34, ST59, ST416 and the novel ST960, by MLST) and E. cloacae clinical strains. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Manageiro, V., Ferreira, E., Louro, D., The Antimicrobial Resistance Surveillance Program in Portugal (ARSIP), Caniça, M. 2013. Polyclonal KPC-3-producing Enterobacteriaceae in Portugal, p. 212-216. In Mendez-Vilas A. (ed). Worldwide Research Efforts in the Fighting against Microbial Pathogens: From Basic Research to Technological Developments. Boca Raton: BrownWalker Press. | pt_PT |
| dc.identifier.isbn | 978-1-61233-636-7 | |
| dc.identifier.uri | http://hdl.handle.net/10400.18/4180 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | BrownWalker Press | pt_PT |
| dc.relation.publisherversion | http://www.brownwalker.com/book/1612336361 | pt_PT |
| dc.subject | Tn4401-KPC-3 | pt_PT |
| dc.subject | IncFrepB | pt_PT |
| dc.subject | Antibiotic Resistance | pt_PT |
| dc.subject | Carbapenemase | pt_PT |
| dc.subject | Resistência aos Antimicrobianos | pt_PT |
| dc.title | Polyclonal KPC-3-producing Enterobacteriaceae in Portugal | pt_PT |
| dc.type | book part | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 216 | pt_PT |
| oaire.citation.startPage | 212 | pt_PT |
| rcaap.rights | closedAccess | pt_PT |
| rcaap.type | bookPart | pt_PT |
