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Advisor(s)
Abstract(s)
O cádmio é um metal pesado tóxico e carcinogénico, que representa uma
ameaça séria para a saúde humana. A população geral pode encontrar-se
exposta ao cádmio por diversas vias e o estudo INSEF-ExpoQuim visou
caracterizar a exposição da população portuguesa adulta (28-39 anos )
a este agente químico através de um estudo transversal. Este estudo
incluiu 295 indivíduos, os quais reponderam a um questionário (dados
sociodemográficos, de estilos de vida e possíveis vias de exposição
) e facultaram uma amostra de urina para quantificação de cádmio
por espectrometria de massa com plasma indutivo acoplado ( ICP-
-MS ). Observou-se uma média geométrica de 0,092 μg Cd/g creatinina
[ IC ( 95%): 0,084-0,101 ], apresentando as mulheres valores mais elevados
( 0,103 vs 0,079 ), bem como os fumadores ( 0,135 vs 0,081).
Cadmium is a toxic and carcinogenic heavy metal, that presents a serious threat to human health. The general population can be exposed through several pathways and the study INSEF-ExpoQuim aimed to characterise the exposure of the Portuguese adult population (28-29 years) to this chemical agent through the development of a cross-sectional study. This study has included 295 individuals, that have answered to a questionnaire (sociodemographic characteristics, lifestyle and possible exposure sources) and provided a urine sample for the quantification of cadmium by inductively coupled plasma mass spectrometry ( ICP-MS). A geometric mean of 0.092 μg Cd/g creatinine [ 95%CI: 0.084-0.101 μg Cd/g creatinine ] was observed, with females ( 0.103 vs 0.079) and smokers ( 0.135 vs 0.081) presenting higher values.
Cadmium is a toxic and carcinogenic heavy metal, that presents a serious threat to human health. The general population can be exposed through several pathways and the study INSEF-ExpoQuim aimed to characterise the exposure of the Portuguese adult population (28-29 years) to this chemical agent through the development of a cross-sectional study. This study has included 295 individuals, that have answered to a questionnaire (sociodemographic characteristics, lifestyle and possible exposure sources) and provided a urine sample for the quantification of cadmium by inductively coupled plasma mass spectrometry ( ICP-MS). A geometric mean of 0.092 μg Cd/g creatinine [ 95%CI: 0.084-0.101 μg Cd/g creatinine ] was observed, with females ( 0.103 vs 0.079) and smokers ( 0.135 vs 0.081) presenting higher values.
Description
Keywords
Cádmio Exposição Humana Biomonitorização Humana Avaliação do Risco Saúde Ambiental INSEF-ExpoQuim Exposição da População Portuguesa a Químicos Ambientais Portugal Genotoxicidade Ambiental
Pedagogical Context
Citation
Boletim Epidemiológico Observações. 2022;11(Supl 14):19-24
Publisher
Instituto Nacional de Saúde Doutor Ricardo Jorge, IP
