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Advisor(s)
Abstract(s)
As alterações climáticas têm sido identificadas como um fator determinante
para a segurança dos alimentos consumidos em todo o mundo. As micotoxinas,
contaminantes alimentares produzidos por fungos, são habitualmente
identificadas como um dos principais perigos neste contexto. As aflatoxinas
assumem particular relevo, face à sua toxicidade aguda e crónica. A região
do Mediterrâneo, incluindo Portugal, tem sido considerada uma região
particularmente vulnerável às consequências das alterações climáticas.
O presente estudo pretende estimar o impacto na saúde da exposição
a aflatoxinas em Portugal e discutir a potencial influência das alterações
climáticas no risco para a saúde associado a esta exposição. Para estimar
o número de casos de carcinoma hepatocelular associados à exposição a
aflatoxinas, foi determinada a fração atribuível da população. Para estimar o
impacto da exposição a aflatoxinas na saúde dos Portugueses, a carga de
doença foi determinada aplicando-se o conceito de anos de vida ajustados
por incapacidade (DALY). É expectável que no futuro, em consequência das
alterações climáticas, o número de DALYs bem como do número de casos
de carcinoma hepatocelular aumente. A quantificação do impacto na saúde
da exposição a aflatoxinas em cenário de alterações climáticas reveste-se
de particular importância, em especial para o desenvolvimento de políticas
e medidas preventivas que possam proteger a população.
Climate change has been indicated as a driver for food safety issues worldwide, mainly due to the impact on the occurrence of food safety hazards at various stages of food chain. Mycotoxins, natural contaminants produced by fungi, are among the most important of such hazards. Aflatoxins, which have the highest acute and chronic toxicity of all mycotoxins, assume particular importance. Mediterranean region, including Portugal, was considered a climate change hotspot. The present study aims to estimate the health impact of aflatoxins exposure in Portugal and to discuss the potential influence of climate change on the health risk associated to this exposure. A population attributable fraction was determined to estimate the number of extra cases of hepatocellular carcinoma (HCC) associated to the Portuguese aflatoxin exposure, and the Disability Adjusted Life Years (DALYs) were derived to estimate the associated burden of disease. It is expected that in the future the number of DALYs and the associated cases of HCC due to aflatoxins exposure will increase due to climate change. The quantification of the health impact associated with exposure to aflatoxins in climate change scenarios presents particular importance, especially for the development of politics and preventive measures to protect human population.
Climate change has been indicated as a driver for food safety issues worldwide, mainly due to the impact on the occurrence of food safety hazards at various stages of food chain. Mycotoxins, natural contaminants produced by fungi, are among the most important of such hazards. Aflatoxins, which have the highest acute and chronic toxicity of all mycotoxins, assume particular importance. Mediterranean region, including Portugal, was considered a climate change hotspot. The present study aims to estimate the health impact of aflatoxins exposure in Portugal and to discuss the potential influence of climate change on the health risk associated to this exposure. A population attributable fraction was determined to estimate the number of extra cases of hepatocellular carcinoma (HCC) associated to the Portuguese aflatoxin exposure, and the Disability Adjusted Life Years (DALYs) were derived to estimate the associated burden of disease. It is expected that in the future the number of DALYs and the associated cases of HCC due to aflatoxins exposure will increase due to climate change. The quantification of the health impact associated with exposure to aflatoxins in climate change scenarios presents particular importance, especially for the development of politics and preventive measures to protect human population.
Description
Keywords
Segurança Alimentar Aflatoxinas Exposição Avaliação do Impacte em Saúde Portugal Saúde Pública
Pedagogical Context
Citation
Boletim Epidemiológico Observações. 2018 maio-agosto;7(22):25-28
Publisher
Instituto Nacional de Saúde Doutor Ricardo Jorge, IP
