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Host factors associated to false negative and indeterminate results in an interferon‐γ release assay in patients with active tuberculosis

dc.contributor.authorSantos, J.A.
dc.contributor.authorDuarte, R.
dc.contributor.authorNunes, C.
dc.date.accessioned2021-03-31T16:37:36Z
dc.date.available2021-03-31T16:37:36Z
dc.date.issued2020-12-13
dc.description.abstractInformation on host factors that contribute to false negative and indeterminate results in interferon-γ release assays (IGRA) are critical to improve the usefulness of these tests in the fight against tuberculosis (TB) epidemics. The aim of this study was to estimate and compare the sensitivity of an IGRA and the tuberculin skin test (TST), independently and as a combined approach, in patients with TB and to identify risk factors associated with false negative and indeterminate IGRA results.pt_PT
dc.description.sponsorshipFundação para a Ciência e Tecnologia provided financial support to conduct this research [Grant: PTDC/SAU-PUB/31346/2017] but had no involvement in the researchitself.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPulmonology. Nov-Dec 2020;26(6):353-362. doi: 10.1016/j.pulmoe.2019.11.001. Epub 2019 Dec 13.pt_PT
dc.identifier.doi10.1016/j.pulmoe.2019.11.001pt_PT
dc.identifier.issn2531-0437
dc.identifier.urihttp://hdl.handle.net/10400.18/7616
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevier/ Sociedade Portuguesa de Pneumologiapt_PT
dc.relationFrom symptoms to diagnosis of Urban Tuberculosis, considering individual and contextual factors. What are the determinants and critical points of this delay?s pathway?
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S2531043719302090?via%3Dihubpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectInterferon-gamma Releasept_PT
dc.subjectTestspt_PT
dc.subjectLatent Tuberculosispt_PT
dc.subjectPreventive Medicinept_PT
dc.subjectPublic Healthpt_PT
dc.subjectTuberculin Testpt_PT
dc.subjectTuberculosispt_PT
dc.subjectInfecções Respiratóriaspt_PT
dc.titleHost factors associated to false negative and indeterminate results in an interferon‐γ release assay in patients with active tuberculosispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleFrom symptoms to diagnosis of Urban Tuberculosis, considering individual and contextual factors. What are the determinants and critical points of this delay?s pathway?
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FSAU-PUB%2F31346%2F2017/PT
oaire.citation.endPage362pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage353pt_PT
oaire.citation.titlePulmonologypt_PT
oaire.citation.volume26pt_PT
oaire.fundingStream3599-PPCDT
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctAcesso de acordo com política editorial da revista.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublication49a7f05c-5c12-4512-b8a6-5771454c143d
relation.isProjectOfPublication.latestForDiscovery49a7f05c-5c12-4512-b8a6-5771454c143d

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