Host factors associated to false negative and indeterminate results in an interferon‐γ release assay in patients with active tuberculosis

Santos, J.A.; Duarte, R.; Nunes, C.

http://hdl.handle.net/10400.18/7616

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Autores

Santos, J.A.

Duarte, R.

Nunes, C.

Resumo(s)

Information on host factors that contribute to false negative and indeterminate results in interferon-γ release assays (IGRA) are critical to improve the usefulness of these tests in the fight against tuberculosis (TB) epidemics. The aim of this study was to estimate and compare the sensitivity of an IGRA and the tuberculin skin test (TST), independently and as a combined approach, in patients with TB and to identify risk factors associated with false negative and indeterminate IGRA results.

Palavras-chave

Interferon-gamma Release Tests Latent Tuberculosis Preventive Medicine Public Health Tuberculin Test Tuberculosis Infecções Respiratórias

URI

http://hdl.handle.net/10400.18/7616

Citação

Pulmonology. Nov-Dec 2020;26(6):353-362. doi: 10.1016/j.pulmoe.2019.11.001. Epub 2019 Dec 13.

Projetos de investigação

From symptoms to diagnosis of Urban Tuberculosis, considering individual and contextual factors. What are the determinants and critical points of this delay?s pathway?

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Editora

Elsevier/ Sociedade Portuguesa de Pneumologia

DOI

10.1016/j.pulmoe.2019.11.001

Coleções

DDI - Artigos em revistas nacionais

Licença CC

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