Host factors associated to false negative and indeterminate results in an interferon‐γ release assay in patients with active tuberculosis

Santos, J.A.; Duarte, R.; Nunes, C.

http://hdl.handle.net/10400.18/7616

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Authors

Santos, J.A.

Duarte, R.

Nunes, C.

Abstract(s)

Information on host factors that contribute to false negative and indeterminate results in interferon-γ release assays (IGRA) are critical to improve the usefulness of these tests in the fight against tuberculosis (TB) epidemics. The aim of this study was to estimate and compare the sensitivity of an IGRA and the tuberculin skin test (TST), independently and as a combined approach, in patients with TB and to identify risk factors associated with false negative and indeterminate IGRA results.