Iron homeostasis in immune mononuclear cells: a potencial role in atherogenesis

Marques, Liliana Alves da Silva

http://hdl.handle.net/10400.18/3077

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Authors

Marques, Liliana Alves da Silva

Abstract(s)

Aims of the study: -Characterize the axis ferroportin-1/oxidase in immune cells: Expression of ceruloplasmin isoforms in lymphocytes and monocytes/macrophages; Subcellular localization and regulation of Ferroportin-1 and its potential partners in macrophages. -Study the effect of pro-inflammatory (M1) and/or atherogenic conditions (Mox) on macrophage iron metabolism.