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Iron homeostasis in immune mononuclear cells: a potencial role in atherogenesis
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Autores
Orientador(es)
Resumo(s)
Aims of the study:
-Characterize the axis ferroportin-1/oxidase in immune cells: Expression of ceruloplasmin isoforms in lymphocytes and monocytes/macrophages; Subcellular localization and regulation of Ferroportin-1 and its potential partners in macrophages.
-Study the effect of pro-inflammatory (M1) and/or atherogenic conditions (Mox) on macrophage iron metabolism.
Descrição
Palavras-chave
Determinantes Imunológicos em Doenças Crónicas Iron Homeostasis
Contexto Educativo
Citação
Editora
Instituto Nacional de Saúde Doutor Ricardo Jorge, IP