Publication
Regulation of glucose transporters by protein kinases in cancer cells
| dc.contributor.author | Henriques, Andreia F. | |
| dc.contributor.author | Matos, Paulo | |
| dc.contributor.author | Jordan, Peter | |
| dc.date.accessioned | 2018-03-13T13:12:59Z | |
| dc.date.available | 2018-03-13T13:12:59Z | |
| dc.date.issued | 2017-10 | |
| dc.description.abstract | Reprogramming of energy metabolism is one of the hallmarks of cancer, since tumour cells need to fuel their high proliferation rates. Warburg et al. first observed that cancer cells largely limit their method of energy production to glycolysis only. In order to compensate for lower ATP yields, cancer cells often upregulate expression of glucose transporters, typically GLUT1, which substantially increases extracellular glucose import into the cytoplasm. | pt_PT |
| dc.description.sponsorship | This work was supported by the Fundação para a Ciência e Tecnologia through a centre grant (UID/MULTI/04046/2013) to BioISI. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | EMJ Oncol. 2017;5[1]:50-52. Abstract Review No. AR9. | pt_PT |
| dc.identifier.doi | 10.1093/annonc/mdx361.036 | pt_PT |
| dc.identifier.issn | 2054-619X | |
| dc.identifier.uri | http://hdl.handle.net/10400.18/5394 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | no | pt_PT |
| dc.publisher | European Medical Journal | pt_PT |
| dc.relation.publisherversion | https://www.emjreviews.com/oncology/abstract/regulation-of-glucose-transporters-by-protein-kinases-in-cancer-cells/ | pt_PT |
| dc.subject | WNK Protein Kinases | pt_PT |
| dc.subject | Colorectal Cancer | pt_PT |
| dc.subject | Tumor Cells | pt_PT |
| dc.subject | WNK Proteina Cinases | pt_PT |
| dc.subject | Transporte de Glucose | pt_PT |
| dc.subject | Vias de Transdução de Sinal e Patologias Associadas | pt_PT |
| dc.subject | Cancro Coloretal | pt_PT |
| dc.title | Regulation of glucose transporters by protein kinases in cancer cells | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 52 | pt_PT |
| oaire.citation.issue | 51 | pt_PT |
| oaire.citation.startPage | 50 | pt_PT |
| oaire.citation.title | European Medical Journal Oncology | pt_PT |
| oaire.citation.volume | [1] | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |