Regulation of glucose transporters by protein kinases in cancer cells

Henriques, Andreia F.; Matos, Paulo; Jordan, Peter

http://hdl.handle.net/10400.18/5394

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Autores

Henriques, Andreia F.

Matos, Paulo

Jordan, Peter

Resumo(s)

Reprogramming of energy metabolism is one of the hallmarks of cancer, since tumour cells need to fuel their high proliferation rates. Warburg et al. first observed that cancer cells largely limit their method of energy production to glycolysis only. In order to compensate for lower ATP yields, cancer cells often upregulate expression of glucose transporters, typically GLUT1, which substantially increases extracellular glucose import into the cytoplasm.

Palavras-chave

WNK Protein Kinases Colorectal Cancer Tumor Cells WNK Proteina Cinases Transporte de Glucose Vias de Transdução de Sinal e Patologias Associadas Cancro Coloretal

URI

http://hdl.handle.net/10400.18/5394

Citação

EMJ Oncol. 2017;5[1]:50-52. Abstract Review No. AR9.

Editora

European Medical Journal

DOI

10.1093/annonc/mdx361.036

Coleções

DGH - Artigos em revistas internacionais

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