NANoREG Deliverable D 5.8 - Decision tree for risk assessment of MNMs

Susan Dekkers, Agnes G. Oomen, Eric A.J. Bleeker, Rob J. Vandebriel, Christian Micheletti, Joan Cabellos, Gemma Janer, Natalia Fuentes, Socorro Vázquez-Campos, Teresa Borges, Maria João Silva, Adriele Prina-Mello, Dania Movia, Fabrice Nesslany, Ana Ribeiro8, Paulo Emílio Leite, Monique Groenewold, Flemming R. Cassee, Adrienne J.A.M. Sips, Aart Dijkzeul, Tom van Teunenbroek, Susan W.P. Wijnhoven

http://hdl.handle.net/10400.18/4618

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Authors

Susan Dekkers, Agnes G. Oomen, Eric A.J. Bleeker, Rob J. Vandebriel, Christian Micheletti, Joan Cabellos, Gemma Janer, Natalia Fuentes, Socorro Vázquez-Campos, Teresa Borges, Maria João Silva, Adriele Prina-Mello, Dania Movia, Fabrice Nesslany, Ana Ribeiro8, Paulo Emílio Leite, Monique Groenewold, Flemming R. Cassee, Adrienne J.A.M. Sips, Aart Dijkzeul, Tom van Teunenbroek, Susan W.P. Wijnhoven

Abstract(s)

In the current report, a new strategy for risk assessment of nanomaterials is described, which builds upon previous project outcomes and is developed within the FP7 NANoREG project. NANoREG has the aim to develop, for the long term, new testing strategies adapted to a high number of nanomaterials where many factors can affect their environmental and health impact. In the proposed risk assessment strategy, approaches for (Quantitative) Structure Activity Relationships ((Q)SARs), grouping and read across are integrated and expanded to guide the user how to prioritise those nanomaterial applications that may lead to high risks for human health.