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Occupational studies developed in Portugal in the scope of HBM4EU – Main results and way forward

2023-06-15Conference object Restricted access
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dc.contributor.authorMartins, Carla
dc.contributor.authorRibeiro, Edna
dc.contributor.authorLadeira, Carina
dc.contributor.authorPinhal, Herminia
dc.contributor.authorNogueira, Ana
dc.contributor.authorReis, Silvia
dc.contributor.authorLouro, Henriqueta
dc.contributor.authorSilva, Maria João
dc.contributor.authorViegas, Susana
dc.date.accessioned2024-02-27T16:49:19Z
dc.date.available2024-02-27T16:49:19Z
dc.date.issued2023-06-15
dc.description.abstractIntroduction: Within the EU human biomonitoring initiative (HBM4EU), targeted national studies on occupational settings, where exposure to chemicals could occur, were performed. These studies aimed to provide information on occupational exposure to chemicals using biomonitoring approaches to support the implementation of new risk management measures (RMM) and policy actions at national and European levels. Methods: Cross-sectional studies were performed in two occupational settings: i) a setting with plating, welding and painting activities, targeting exposure to chromium VI [Cr(VI)]; and ii) a setting dedicated to processing of electronic waste (e-waste), targeting exposure to metals. Both studies included a control group obtained from the Portuguese general population, employed in different companies with no known exposure to Cr(VI) or involvement on tasks related with recycling of e-waste. Studies enrolled 50 workers and 27 controls (chromates study) and 26 workers and 12 controls (e-waste study). Spot urine samples were collected in the beginning and the end of the work week, and concentrations of metals were determined. Protocols were submitted to Ethics Committees with the approvals being granted before recruiting the studies’ participants (companies and workers). Descriptive statistical analysis was performed as well as inferential analysis (Wilcoxon test, Mann–Whitney test, and Kruskal–Wallis test). Results: Regarding chromates study, median levels obtained for workers were 0.33 µg/g crea for Cr, in the post-shift samples. Results showed that painters presented higher levels of Cr in post-shift urine samples than the control group (p<0.05), although not presenting differences between pre-shift and post-shift urine samples (p>0.05). Platers showed higher levels of Cr in post-shift urine samples when compared to pre-shift samples (p<0.05). Welders did not present statistically significant differences between pre- and post-shift samples and in relation to control group (p>0.05). Regarding RMM, the use of respiratory protection equipment by painters was identified as a promotor of lower exposures (p<0.05). Regarding e-waste study, median levels obtained for workers were 0.21, 0.43 and 12.70 µg/g crea for cadmium (Cd), mercury (Hg) and lead (Pb), respectively, in the post-shift samples. Statistically significant differences between workers and control group were found for urinary Pb levels (p<0.05), and no significant differences were found between pre- and post-shift urine samples for Cd, Hg and Pb. Conclusions: The results obtained showed that workers are exposed to metals in these occupational settings, thus, RMM in place need to be improved. Based on the results obtained, the implementation and enforcement of new regulatory actions should be considered. The results also claim attention for the need of updating the occupational limit values as it is being discussed at European level for Cr(VI), Pb and Cd due to the related health effects [3]. The differentiated data provided by biomonitoring tools demonstrated that these should be used more often to perform exposure assessment.pt_PT
dc.description.sponsorshipH2020 no 733032pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/9147
dc.language.isoengpt_PT
dc.peerreviewednopt_PT
dc.relationEuropean Human Biomonitoring Initiative
dc.subjectChromium Hexavalentpt_PT
dc.subjectHuman Biomonitoringpt_PT
dc.subjectExposure Assessmentpt_PT
dc.subjectE-wastept_PT
dc.subjectEnvironmental Genotoxicitypt_PT
dc.subjectGenotoxicidade Ambientalpt_PT
dc.subjectHBM4EUpt_PT
dc.subjectPortugalpt_PT
dc.titleOccupational studies developed in Portugal in the scope of HBM4EU – Main results and way forwardpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleEuropean Human Biomonitoring Initiative
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/733032/EU
oaire.citation.conferencePlaceLisboa, Portugalpt_PT
oaire.citation.title23º Congresso de Saúde Pública, 15-16 junho 2023pt_PT
oaire.fundingStreamH2020
person.familyNameLouro
person.familyNameSilva
person.givenNameHenriqueta
person.givenNameMaria Joao
person.identifier157627
person.identifier.ciencia-id721D-2BB1-7DB1
person.identifier.ciencia-id7710-643D-97A3
person.identifier.orcid0000-0001-9744-7332
person.identifier.orcid0000-0002-6060-0716
person.identifier.scopus-author-id6507971479
person.identifier.scopus-author-id55944437600
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameEuropean Commission
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication2361a951-8b9a-4b90-92d6-f6384003a242
relation.isAuthorOfPublicationa7763685-7c34-468d-b958-9dd0aca66db4
relation.isAuthorOfPublication.latestForDiscovery2361a951-8b9a-4b90-92d6-f6384003a242
relation.isProjectOfPublication6815dc2d-ef7e-4535-8dd3-5193c8bffba5
relation.isProjectOfPublication.latestForDiscovery6815dc2d-ef7e-4535-8dd3-5193c8bffba5

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