A carregar...
Publicação
High throughput toxicity screening and intracellular detection of nanomaterials
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 6.22 MB | Adobe PDF |
Orientador(es)
Resumo(s)
With the growing numbers of nanomaterials (NMs), there is a great demand for
rapid and reliable ways of testing NM safety—preferably using in vitro
approaches, to avoid the ethical dilemmas associated with animal research. Data
are needed for developing intelligent testing strategies for risk assessment of
NMs, based on grouping and read-across approaches. The adoption of high
throughput screening (HTS) and high content analysis (HCA) for NM toxicity
testing allows the testing of numerous materials at different concentrations and
on different types of cells, reduces the effect of inter-experimental variation, and
makes substantial savings in time and cost.
Descrição
EC FP7 NANoREG (Grant Agreement NMP4-LA-2013-310584)
Free PMC Article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215403/
Free PMC Article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215403/
Palavras-chave
Nanotoxicology High Throughput Genotoxicidade Ambiental
Contexto Educativo
Citação
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Jan;9(1). doi: 10.1002/wnan.1413. Epub 2016 Jun 7
Editora
Wiley/WIREs Nanomedicine and Nanobiotechnology