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Advisor(s)
Abstract(s)
O nĂquel Ă© um elemento natural da superfĂcie terrestre. A alimentação Ă© uma
das principais fontes de exposição a este metal. Devido à sua acumulação no
organismo pode causar efeitos nocivos para a saĂșde como a carcinogĂ©nese
e a dermatite induzida. O principal objetivo deste trabalho foi a determinação
de nĂquel em alimentos analisados como consumidos e representativos da
dieta portuguesa. A metodologia escolhida para a quantificação deste contaminante
foi a espectrometria de massa acoplada a plasma indutivo (ICP-MS)
precedida por digestĂŁo ĂĄcida em vaso fechado no micro-ondas. Foram recolhidas
1560 amostras, que foram analisadas em 130 pools, contendo cada
12 alimentos idĂȘnticos. O teor de nĂquel variou entre 21,2 ÎŒg/kg (sumos) e
1050 ÎŒg/kg (bivalves). O limite de quantificação do mĂ©todo foi o parĂąmetro
analĂtico considerado indicador para a avaliação da exposição. A anĂĄlise
comparativa entre os valores analĂticos superiores ao limite de quantificação
do método e os valores não quantificåveis, demonstrou que todos os pratos
compostos apresentaram valores superiores ao limite de quantificação e
60% dos resultados encontrados nos laticĂnios eram inferiores ao limite de
quantificação do método. Atendendo aos procedimentos aplicados, os resultados
obtidos podem ser utilizados como fonte de informação cientĂfica para
simulaçÔes da avaliação do risco de exposição ao nĂquel, com consequentes
ganhos em saĂșde.
Nickel is a natural element of the earth's crust. Food is one of the main sources of human exposure to this metal. Its accumulation in the body can cause harmful effects to health such as carcinogenesis or induced dermatitis. The aim of this work was the determination of nickel in foodstuffs analyzed as consumed and representative of the Portuguese diet. The methodology chosen for the quantification of this contaminant was inductively coupled plasma mass spectrometry (ICP-MS) preceded by acid digestion in closed vessel microwave digestion. In total 1560 samples were collected and then analyzed into 130 pools, each containing 12 identical foods. The nickel content varied between 21,2 ÎŒg/kg (juices) and 1050 ÎŒg/kg (bivalve). The limit of quantification of the method was the analytical parameter considered as a critical indicator to estimate the lower-bound of contamination and exposure of food. The comparative analysis between the analytical values above the limit of quantification and the unquantifiable values showed that all composites had values higher than the limit of quantification while 60% of the results found in dairy products were below that limit. Taking into account the procedures applied, the results can be used as a source of scientific information for nickel exposure risk assessment simulations, with consequent health gains.
Nickel is a natural element of the earth's crust. Food is one of the main sources of human exposure to this metal. Its accumulation in the body can cause harmful effects to health such as carcinogenesis or induced dermatitis. The aim of this work was the determination of nickel in foodstuffs analyzed as consumed and representative of the Portuguese diet. The methodology chosen for the quantification of this contaminant was inductively coupled plasma mass spectrometry (ICP-MS) preceded by acid digestion in closed vessel microwave digestion. In total 1560 samples were collected and then analyzed into 130 pools, each containing 12 identical foods. The nickel content varied between 21,2 ÎŒg/kg (juices) and 1050 ÎŒg/kg (bivalve). The limit of quantification of the method was the analytical parameter considered as a critical indicator to estimate the lower-bound of contamination and exposure of food. The comparative analysis between the analytical values above the limit of quantification and the unquantifiable values showed that all composites had values higher than the limit of quantification while 60% of the results found in dairy products were below that limit. Taking into account the procedures applied, the results can be used as a source of scientific information for nickel exposure risk assessment simulations, with consequent health gains.
Description
Keywords
NĂquel Alimentação Total Diet Study Avaliação do Risco Segurança Alimentar Portugal
Pedagogical Context
Citation
Boletim Epidemiológico ObservaçÔes. 2016 setembro-dezembro;5(17):10-13
Publisher
Instituto Nacional de SaĂșde Doutor Ricardo Jorge, IP
