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COVID-19 Vaccine Effectiveness Against Hospitalization in Older Adults, VEBIS Hospital Network, Europe, September 2024-May 2025

2025-11-25Artigo científico Acesso aberto
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datacite.subject.fosCiências Médicas
datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg17:Parcerias para a Implementação dos Objetivos
dc.contributor.authorRojas-Castro, Madelyn
dc.contributor.authorVerdasca, Nuno
dc.contributor.authorMonge, Susana
dc.contributor.authorDe Mot, Laurane
dc.contributor.authorTrobajo-Sanmartín, Camino
dc.contributor.authorDuffy, Róisín
dc.contributor.authorTúri, Gergő
dc.contributor.authorKuliese, Monika
dc.contributor.authorDuerrwald, Ralf
dc.contributor.authorBorg, Maria-Louise
dc.contributor.authorPopovici, Odette
dc.contributor.authorGomez, Verónica
dc.contributor.authorMakarić, Zvjezdana Lovrić
dc.contributor.authorLaunay, Odile
dc.contributor.authorMarques, Diogo F.P.
dc.contributor.authorPozo, Francisco
dc.contributor.authorWitdouck, Arne
dc.contributor.authorMartínez-Baz, Iván
dc.contributor.authorFitzgerald, Margaret
dc.contributor.authorOroszi, Beatrix
dc.contributor.authorJančorienė, Ligita
dc.contributor.authorBuda, Silke
dc.contributor.authorDziugyte, Ausra
dc.contributor.authorLazăr, Mihaela
dc.contributor.authorMachado, Ausenda
dc.contributor.authorTabain, Irena
dc.contributor.authorNguyen, Liem Binh Luong
dc.contributor.authorWagner, Eva Rivas
dc.contributor.authorDufrasne, François
dc.contributor.authorCastilla, Jesús
dc.contributor.authorDomegan, Lisa
dc.contributor.authorVelkey, Viktória
dc.contributor.authorMajauskaite, Fausta
dc.contributor.authorHackmann, Carolin
dc.contributor.authorNicolay, Nathalie
dc.contributor.authorBacci, Sabrina
dc.contributor.authorRose, Angela M.C.
dc.contributor.authorEuropean Hospital Vaccine Effectiveness Group
dc.date.accessioned2026-01-13T12:23:08Z
dc.date.available2026-01-13T12:23:08Z
dc.date.issued2025-11-25
dc.description.abstractWe estimated COVID-19 vaccine effectiveness (VE) against PCR-confirmed SARS-CoV-2 hospitalization in patients ≥ 60 years with severe acute respiratory infection, using a multicenter, test-negative, case-control study across seven sites in six European countries between September 2024 and May 2025. We included 352 cases (115 vaccinated; 33%) and 9980 controls (5024 vaccinated; 50%). VE was 42% (95% CI: 15; 61) 14-59 days post-vaccination, 32% (95% CI: -1; 54) at 60-119 days, and 36% (95% CI: 2; 60) at 120-179 days, and no effect thereafter. Among adults aged 60-79 and ≥ 80 years, we observed moderate VE against COVID-19 hospitalization for up to 2 and 4 months, respectively.eng
dc.description.sponsorshipThe Vaccine Effectiveness, Burden and Impact Studies (VEBIS) is a project of the European Centre for Disease Prevention and Control, run under the framework contract No. ECDC/2021/016 (EU-H).
dc.identifier.citationInfluenza Other Respir Viruses. 2025 Nov;19(11):e70191. doi: 10.1111/irv.70191
dc.identifier.doi10.1111/irv.70191
dc.identifier.eissn1750-2659
dc.identifier.issn1750-2640
dc.identifier.pmid41290396
dc.identifier.urihttp://hdl.handle.net/10400.18/10684
dc.language.isoeng
dc.peerreviewedyes
dc.publisherWiley
dc.relation.hasversionhttps://onlinelibrary.wiley.com/doi/10.1111/irv.70191
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectCase–Control Study
dc.subjectElderly
dc.subjectSevere Acute Respiratory Infection (SARI)
dc.subjectTest‐Negative Design
dc.subjectVaccine Effectiveness
dc.subjectVEBIS
dc.subjectCOVID-19
dc.subjectInfecções Respiratórias
dc.subjectEstados de Saúde e da Doença
dc.subjectCuidados de Saúde
dc.titleCOVID-19 Vaccine Effectiveness Against Hospitalization in Older Adults, VEBIS Hospital Network, Europe, September 2024-May 2025eng
dc.typejournal article
dcterms.referenceshttps://onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1111%2Firv.70191&file=irv_70191-sup-0001-Supplementary.docx
dspace.entity.typePublication
oaire.citation.issue11
oaire.citation.startPagee70191
oaire.citation.titleInfluenza and Other Respiratory Viruses
oaire.citation.volume19
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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