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Publicação
COVID-19 Vaccine Effectiveness Against Hospitalization in Older Adults, VEBIS Hospital Network, Europe, September 2024-May 2025
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Orientador(es)
Resumo(s)
We estimated COVID-19 vaccine effectiveness (VE) against PCR-confirmed SARS-CoV-2 hospitalization in patients ≥ 60 years with severe acute respiratory infection, using a multicenter, test-negative, case-control study across seven sites in six European countries between September 2024 and May 2025. We included 352 cases (115 vaccinated; 33%) and 9980 controls (5024 vaccinated; 50%). VE was 42% (95% CI: 15; 61) 14-59 days post-vaccination, 32% (95% CI: -1; 54) at 60-119 days, and 36% (95% CI: 2; 60) at 120-179 days, and no effect thereafter. Among adults aged 60-79 and ≥ 80 years, we observed moderate VE against COVID-19 hospitalization for up to 2 and 4 months, respectively.
Descrição
Palavras-chave
Case–Control Study Elderly Severe Acute Respiratory Infection (SARI) Test‐Negative Design Vaccine Effectiveness VEBIS COVID-19 Infecções Respiratórias Estados de Saúde e da Doença Cuidados de Saúde
Contexto Educativo
Citação
Influenza Other Respir Viruses. 2025 Nov;19(11):e70191. doi: 10.1111/irv.70191
Editora
Wiley