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Human biomonitoring of mycotoxins under HBM4EU: update on key outputs

2021-05Conference object Restricted access
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dc.contributor.authorAlvito, Paula
dc.contributor.authorAssunção, Ricardo
dc.contributor.authorBajard, Lola
dc.contributor.authorMol, Hans
dc.contributor.authorMartins, Carla
dc.contributor.authorMengelers, Marcel
dc.contributor.authorNamorado, Sónia
dc.contributor.authorVasco, Elsa
dc.contributor.authorVan den Brand, Annick
dc.contributor.authorViegas, Susana
dc.contributor.authorSilva, Maria
dc.date.accessioned2022-07-10T18:54:31Z
dc.date.available2022-07-10T18:54:31Z
dc.date.issued2021-05
dc.description.abstractThe European Human Biomonitoring Initiative (HBM4EU) is a project gathering 30 countries, funded under Horizon 2020 and running from 2017 until 2021. The goal of HBM4EU is to generate evidence on the current exposure of European citizens to chemicals and on their possible health effects to assess the associated risks. Following a systematic prioritization exercise, the mycotoxins Deoxynivalenol (DON) and Fumonisin B1 (FB1) were considered as priority substances around which the HBM4EU research programme was developed. As part of the HBM4EU project, several policy questions are being addressed for these mycotoxins, concerning analytical methods, exposure levels and high exposure population groups in Europe (including workers), associated time trends, risk characterization, exposure models and toxicokinetic data, human biomonitoring guidance values, key events that determine the health effects of the target mycotoxins, effect biomarkers, data gaps and research needs. Key outputs from HBM4EU achieved until now for DON and FB1, include: i) a biomarker selected to assess human exposure to DON (total urinary DON) that will be used in the aligned studies, ii) several European laboratories selected to perform DON analysis after passing an interlaboratory study, ii) a research protocol on human exposure and geographic variations in Europe, iv) a risk assessment plan to assess DON and FB1 exposure in Europe, v) a review of available toxicokinetics models, vi) a draft on the possible mechanisms of FB1-induced adverse health effects and vii) a specific effect biomarker for FB1.pt_PT
dc.description.sponsorshipWork co-funded by the HBM4EU project, Grant Agreement No: 733032 and by Portuguese national funds: FCT/MCTES through CESAM (UIDP/50017/2020 + UIDB/50017/2020) and ToxOmics (UIDB/00009/2020 & UIDP/00009/2020).pt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/8214
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationEuropean Human Biomonitoring Initiative
dc.relationCentre for Environmental and Marine Studies
dc.relationCentre for Environmental and Marine Studies
dc.relationCentre for Toxicogenomics and Human Health
dc.relationCentre for Toxicogenomics and Human Health
dc.subjectSegurança Alimentarpt_PT
dc.subjectComposição dos Alimentospt_PT
dc.subjectSaúde Humanapt_PT
dc.subjectAvaliação do Riscopt_PT
dc.subjectHuman Biomonitoringpt_PT
dc.subjectGenómica Funcionalpt_PT
dc.subjectGenómica Funcional e Estruturalpt_PT
dc.titleHuman biomonitoring of mycotoxins under HBM4EU: update on key outputspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleEuropean Human Biomonitoring Initiative
oaire.awardTitleCentre for Environmental and Marine Studies
oaire.awardTitleCentre for Environmental and Marine Studies
oaire.awardTitleCentre for Toxicogenomics and Human Health
oaire.awardTitleCentre for Toxicogenomics and Human Health
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/733032/EU
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50017%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50017%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00009%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00009%2F2020/PT
oaire.citation.conferencePlace(online)pt_PT
oaire.citation.title42nd Mycotoxin Workshop, Web conference, May 31 - June 02, 2021pt_PT
oaire.fundingStreamH2020
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameEuropean Commission
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isProjectOfPublication6815dc2d-ef7e-4535-8dd3-5193c8bffba5
relation.isProjectOfPublication4e22de31-8fc5-4b15-b980-3fd0edf5515d
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relation.isProjectOfPublication.latestForDiscovery6815dc2d-ef7e-4535-8dd3-5193c8bffba5

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