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Publicação
Pharmacogenomics of dyslipidaemia drugs in Portugal
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Autores
Orientador(es)
Resumo(s)
Background/Aim: Statins are the standard treatment for dyslipidaemia disorders, but there is a
wide (10-70%) variation in patient response to statin treatment and several
documented serious adverse effects. Studies of variants in genes regulating
drug absorption, metabolism, pharmacodynamics and excretion mechanisms,
have been implicated as reasons for this variability.
The aim of this study is to determine the prevalence of pharmacogenetic
relevant genotypes in the Portuguese population and in a sample of high
cardiovascular risk patients: familial hypercholesterolemia subjects.
Descrição
Palavras-chave
Pharmacogenomics Dyslipidemia Portugal e_COR Familial Hypercholesterolaemia Doenças Cardio e Cérebro-vasculares
Contexto Educativo
Citação
Editora
Instituto Nacional de Saúde Doutor Ricardo Jorge, IP