Toxicity of different classes of manufactured naomaterials in alveolar epithelial cells

Brandão, Fátima; Fraga, Sónia; Costa, Carla; Bessa, Maria João; Haase, Andrea; Teixeira, João Paulo

http://hdl.handle.net/10400.18/6085

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Abstract(s)

The toxicological assessment of the potential toxicity of manufactured nanomaterials (MNMs) is urgently needed due to their increased use for commercial and industrial applications. Thus, this study evaluated the cyto- and genotoxicity of a panel of MNMs, including SiO2 NPs, graphene oxide, and nano-sized pigments in rat alveolar epithelial cells (RLE-6TN), a primary target during inhalation exposure.