Browsing by Issue Date, starting with "2022-09-16"
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- Definition of an AOP landscape for ingested NMsPublication . Rolo, Dora; Silva, Maria João; Louro, HenriquetaAbout definition of an Adverse Outcome Pathway landscape for ingested nanomaterials
- Nanocellulose effects on microRNA expression in human bronchial epithelial cellsPublication . Ventura, Célia; Vieira, Luís; Silva, Catarina; Pinto, Fátima; Pedrosa, J.F.S.; Fernandes, S.; Raupp da Rosa, R.; Godinho, M.H.; Ferreira, P.J.T.; Louro, Henriqueta; Silva, Maria JoãoNanocellulose is an innovative nanomaterial with physicochemical properties (high specific area, high tensile strength and stiffness, gas barrier properties, optical properties, and biodegradability) that give it potential for a wide variety of industrial (packaging, paper industry and others) and biomedical applications (regenerative medicine, wound healing, drug delivery systems and others).
- ToxApp4nanoCELFI – integrated view on the safety assessment of nanocellulosesPublication . Silva, Maria JoãoBackground: The expanding production and application of cellulose nanofibrils (CNF) has increased the risk of human exposure (workers and consumers); It is mandatory to ensure the safety of CNF for human health and the environment in a costeffective way – relevant to public and occupational health and also to industries; Because CNF are nanofibers with a high aspect ratio like MWCNT and crocidolite, the main question is whether some of the CNF synthesized may have deleterious effects on human health; Limited toxicological data is available for CNF given that most studies have focused on bacterial or nanocrystalline celulose; A previous study by the team showed that a CNF produced by TEMPO-mediated oxidation of an industrial bleached Eucalyptus globulus kraft pulp was genotoxic to alveolar cells (Ventura et al., 2018); The assessment of potential toxic effects of the newly synthesized CNF must be addressed in an early phase of the value chain to allow changes to be made before the production scale up (the safer-by-design approach).
- Nanotoxicology in Safety Assessment of Nanomaterials: Book PresentationPublication . Louro, Henriqueta; Silva, Maria JoãoPresentation of the book 'Nanotoxicology in Safety Assessment of Nanomaterials' (https://link.springer.com/book/10.1007/978-3-030-88071-2): Worldwide experts present the latest knowledge on nanotoxicology Innovative approaches in synthesis/application of nanomaterials Provides central knowledge for applying safe and sustainable nanotechnologies with a safe-by-design” approach
- Cellular, Molecular and Genotoxic Effects of Digested Titanium Dioxide NanomaterialsPublication . Louro, HenriquetaAbout Cellular, Molecular and Genotoxic Effects of Digested Titanium Dioxide Nanomaterials.
- Investigation of potential respiratory adverse effects of micro/nanofibrillated cellulose and cellulose nanocrystals using human lung cell linesPublication . Pinto, Fátima; Louro, Henriqueta; Silva, Maria JoãoAbout cellulose nanomaterials (CNMs).
- Toxicological assessment of cellulose nanomaterials: focus on oral exposurePublication . Vital, Nádia; Kranendonk, Michel; Louro, HenriquetaAbout cellulose nanomaterials (CNMs).