Browsing by Author "Henriques, Andreia F."
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- Regulation of glucose transporters by protein kinases in cancer cellsPublication . Henriques, Andreia F.; Matos, Paulo; Jordan, PeterReprogramming of energy metabolism is one of the hallmarks of cancer, since tumour cells need to fuel their high proliferation rates. Warburg et al. first observed that cancer cells largely limit their method of energy production to glycolysis only. In order to compensate for lower ATP yields, cancer cells often upregulate expression of glucose transporters, typically GLUT1, which substantially increases extracellular glucose import into the cytoplasm.