Percorrer por autor "Cassee, Flemming"
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- In vitro toxicity of ceramic nanoparticles in 3D human airway epithelial culturesPublication . Bessa, Maria João; Brandão, Fátima; Salmatonidis, Apostolos; Vulpoi, Adriana; Viana, Mar; Cassee, Flemming; Fraga, Sónia; Teixeira, João PauloThis study aimed to investigate the in vitro toxicity of engineered (ENP) and airborne ceramic NP in a 3D human bronchial epithelial model (MucilAir™) under air-liquid interface conditions.
- Moving towards an advanced method to assess the toxicity of ceramic nanoparticles in human alveolar epithelial cellsPublication . Bessa, Maria João; Brandão, Fátima; Fokkens, Paul; Boere, John; Leseman, Daan; Salmatonidis, Apostolos; Viana, Mar; Cassee, Flemming; Teixeira, João Paulo; Fraga, SóniaThe aim of this study was to investigate the in vitro toxicity of three ceramic nanoparticles in A549 cell line, a primary target during inhalation exposure.
- Pairwise toxicity evaluation of ceramic nanoparticles in submerged and air-liquid interface cultures of human alveolar epithelial A549 cellsPublication . Bessa, Maria João; Fraga, Sónia; Brandão, Fátima; Fokkens, Paul; Boere, J.; Leseman, D.; Salmatonidis, A.; Viana, Mar; Cassee, Flemming; Teixiera, João PauloObjectives: To investigate the in vitro toxicity of ceramic NPs (CeO2, ZrO2 and Sb2O3•SnO2 NPs) in human alveolar epithelial cells, a primary target during inhalation exposure, in both submerged and air-liquid cell cultures
- Toxicity assessment of engineered and airborne process-generated nanoparticles in human alveolar epithelial A549 cellsPublication . Bessa, Maria João; Fraga, Sónia; Brandão, Fátima; Salmatonidis, A.; Viana, Mar; Cassee, Flemming; Teixeira, João PauloNanotechnology offers many possibilities in the ceramic sector by providing innovation of the industrial processes and products. However, nanoparticles (NPs) used in the manufacture of ceramic goods or released to the workplace air during production may pose a serious hazard for human health. This study aimed to investigate in vitro toxicity of both engineered (ENPs) (ZrO2, CeO2, SnO2 and Sb2O3•SnO2) and process-generated nanoparticles (PGNPs) [released during High Velocity Oxy-Fuel (HVOF) spraying] in human alveolar epithelial cells, a primary target following inhalation exposure.
- Toxicity of ceramic nanoparticles in human alveolar epithelial A549 cells at air-liquid interfacePublication . Fraga, Sónia; Bessa, Maria João; Brandão, Fátima; Fokkens, Paul; Salmatonidis, A.; Viana, Mar; Cassee, Flemming; Teixeira, João PauloSeveral ceramic industries have already incorporated within their production processes the manufacture of different types of ceramic nanoparticles (NPs), as well as the application of those nanomaterials on conventional products, which increases the risk of human exposure to these nanoparticles, particularly in occupational settings. The aim of this study was to investigate the in vitro toxicity of ceramic NPs (ZrO2, CeO2 and Sb2O3•SnO2 NPs) in human alveolar epithelial cells, a primary target following inhalation exposure.