DSA - Posters/abstracts em congressos internacionais
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Browsing DSA - Posters/abstracts em congressos internacionais by Author "Abreu, A."
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- The impact of an acute exercise challenge on DNA damage: an human interventionPublication . Duarte, A.; Abreu, A.; Silva, D.; Carvalho, J.; Montanha, T.; Moreira, A.; Teixeira, J. P.; Costa, C.Even though it is commonly accepted that a regular physical activity along with a healthy diet brings positive health-related outcomes, it also seems to be related to several alterations in the human metabolism, organs, cells and deoxyribonucleic acid (DNA). Indeed, there is consistent evidence supporting that above a certain level of intensity and duration, exercise may induce an increase in the generation of reactive oxygen species (ROS). The aim of this study was to analyse the immediate impact of an acute exercise challenge on human’s DNA damage, taking into account their individual characteristics and fitness levels.
- Wildland firefighters: DNA damage and oxidative stress assessmentPublication . Abreu, A.; Duarte, A.; Silva, S.; Morais, S.; Pereira, M.C.; Fernandes, A.; Teixeira, J.P.; Costa, S.Portugal is a high risk country for forest fires. In 2013 alone, Portugal forests accounted for more than 50% of the total burned area of Southern Europe. Portuguese firefighting is supported by a human force of 30.000 firefighters. Firefighters are often exposed to many toxic combustion products, including known carcinogens (benzene, vinyl chloride, formaldehyde, polychlorinated biphenyls, particulate matter). IARC classifies firefighting (or occupational exposure as firefighters) as possible carcinogenic to humans (Group 2b). Epidemiological studies suggest that firefighters have an elevated risk of developing cardiovascular and respiratory diseases and various types of cancer. Biomonitoring data are limited, inconsistent and inconclusive. Genotoxicity evaluation is a valuable tool for studying the most important occupational hazards allowing a reasonable epidemiological evaluation of cancer prediction. The aim of this study was to evaluate DNA damage, total and oxidative, in Portuguese wildland firefighters when compared with the general population.