The impact of an acute exercise challenge on DNA damage: an human intervention

Duarte, A.; Abreu, A.; Silva, D.; Carvalho, J.; Montanha, T.; Moreira, A.; Teixeira, J. P.; Costa, C.

http://hdl.handle.net/10400.18/4572

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Even though it is commonly accepted that a regular physical activity along with a healthy diet brings positive health-related outcomes, it also seems to be related to several alterations in the human metabolism, organs, cells and deoxyribonucleic acid (DNA). Indeed, there is consistent evidence supporting that above a certain level of intensity and duration, exercise may induce an increase in the generation of reactive oxygen species (ROS). The aim of this study was to analyse the immediate impact of an acute exercise challenge on human’s DNA damage, taking into account their individual characteristics and fitness levels.