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Occupational Exposure to formaldehyde in pathology laboratories

dc.contributor.authorPires, Ana Filipa
dc.contributor.authorPais, Aida
dc.contributor.authorFaria, Tiago
dc.contributor.authorPinhal, Hermínia
dc.contributor.authorSilva, Susana
dc.contributor.authorNogueira, Ana
dc.date.accessioned2019-02-28T15:07:49Z
dc.date.available2019-02-28T15:07:49Z
dc.date.issued2018-10-25
dc.description.abstractOccupational exposure to formaldehyde by inhalation causes irritation of the mucous membranes of the eye and upper respiratory tract (nose and throat), leading to tingling, redness or burns to the nose and throat, nasal discharge and watery eyes. At concentrations below 1 ppm symptoms are usually negligible, but they become disturbing when concentrations exceed 2 to 3 ppm. According to IARC, continuous occupational exposure to formaldehyde causes cancer of the nasopharynx and leukemia. IARC classified formaldehyde in group 1 (carcinogenic to humans) in 2004. Formaldehyde is used worldwide, mainly in the production of resins and adhesives used in wood, paper, plastic and textile industry. It is also used in aqueous solutions as a disinfectant and preservative in embalming activities and pathology laboratories. Pathology laboratories receive organ, tissue, or cell specimens collected from humans to study their structural alterations and to serve as support in the diagnosis and prognosis. The main steps are the preparation of formaldehyde solutions, macroscopy, placing the samples in cassettes and microscopic observation. Supporting tasks, necessary to laboratory operation, are emptying and maintenance of the parts prepared, elimination of specimens, recycling or elimination of the waste formaldehyde solutions. Based on results obtained in routine exposure evaluations, formaldehyde concentrations in Portuguese pathology laboratories are not always negligible, so it is important to share them in order to raise awareness to the problem.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/6000
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectExposure to Formaldehydept_PT
dc.subjectPathology Laboratoriespt_PT
dc.subjectOccupational Exposurept_PT
dc.titleOccupational Exposure to formaldehyde in pathology laboratoriespt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceMatosinhos, Porto, Portugalpt_PT
oaire.citation.titleICOETOX 2018 - 4th International Congress on Occupational & Environmental Toxicology, 24-26 October 2018pt_PT
person.familyNameNogueira
person.givenNameAna
person.identifier.orcid0000-0002-4957-6778
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication83daef8b-d84a-48f7-8816-0a672390701c
relation.isAuthorOfPublication.latestForDiscovery83daef8b-d84a-48f7-8816-0a672390701c

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