Repository logo
 
Publication

Nanotoxicology and nanotechnology interplay towards a safe and responsible innovation

2017-07-04Conference object Restricted access
Simple item page
dc.contributor.authorSilva, Maria João
dc.contributor.authorVentura, Célia
dc.contributor.authorDias, Kamila
dc.contributor.authorSaruga, Andreia
dc.contributor.authorPinhão, Mariana
dc.contributor.authorLouro, Henriqueta
dc.date.accessioned2018-03-05T11:27:11Z
dc.date.available2018-03-05T11:27:11Z
dc.date.issued2017-07-04
dc.description.abstractThe European Union Strategic and Action Plan for Nanosciences and Nanotechnologies emphasizes the need of ensuring the development of safe, integrated, and responsible nanotechnologies and nanotechnology products. Indeed, although the use of manufactured nanomaterials (NM) is widespread and has been considered greatly beneficial for several scientific and technological areas, uncertainties about their safety still remain, representing a challenge to scientists, risk assessors and regulators. Recent studies of the team have been aimed at assessing the potential deleterious effects, e.g., genotoxicity that is intimately associated with carcinogenicity, of several classes of NM, using complementary in vitro and in vivo approaches, nested within the conventional risk assessment paradigm. Overall, the results have suggested that specific physicochemical properties of NM are crucial to define their nano-bio interactions and their toxic potential. Furthermore, our findings reinforced previous reports suggesting that factors inherent to experimental conditions and methodologies may affect the effects observed. These and other nano-specific issues have been hindering the categorization of NM according to their toxicity and, consequently, their risk assessment and management. Nonetheless, considering the wide array of NM produced or under development, a case-by-case approach to the risks of each NM seems an unreasonably extensive task. Thus, the development of high-throughput omics-based tools adapted for the toxicity assessment of NM and, on the other hand, the elucidation of the cellular and molecular mechanisms underlying NM toxicity is of utmost importance to progress faster in the field of nanotoxicology. Such information will allow the development of cost-efficient screening strategies and promote predictive nanotoxicology, driving the synthesis of safer NM. The ultimate goal is fostering a sustainable and safe innovation in the field of nanotechnologies.pt_PT
dc.description.sponsorshipEuropean Union Seventh Framework Programme (FP7/2007-2013) under the project NANoREG (grant agreement 310584), the Fundação para a Ciência e Tecnologia (UID/BIM/00009/2013) and by Instituto Nacional de Saúde Doutor Ricardo Jorge, IP.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/5154
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relationA common European approach to the regulatory testing of nanomaterials
dc.subjectNanotechnologypt_PT
dc.subjectNanomaterialspt_PT
dc.subjectToxicologypt_PT
dc.subjectGenotoxicidade Ambientalpt_PT
dc.titleNanotoxicology and nanotechnology interplay towards a safe and responsible innovationpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleA common European approach to the regulatory testing of nanomaterials
oaire.awardURIinfo:eu-repo/grantAgreement/EC/FP7/310584/EU
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FBIM%2F00009%2F2013/PT
oaire.citation.conferencePlaceLisboa, Portugalpt_PT
oaire.citation.titleCiência 2017 - Encontro com a Ciência e Tecnologia em Portugal, 3-5 julho 2017pt_PT
oaire.fundingStreamFP7
oaire.fundingStream5876
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameEuropean Commission
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isProjectOfPublicationf9fe5c15-606f-4958-ac4b-8109981d34c7
relation.isProjectOfPublicatione9cc9728-4f09-4e3a-b30d-53d4429986fb
relation.isProjectOfPublication.latestForDiscoveryf9fe5c15-606f-4958-ac4b-8109981d34c7

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Encontro Ciencia Silva MJS 2017 07 04.pdf
Size:
1.06 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

DGH - Apresentações orais em encontros nacionais