A carregar...
Publicação
Association of a genetic variant in the ALOX5AP with higher risk of ischemic stroke: a case-control, meta-analysis and functional study
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 206.95 KB | Adobe PDF |
Orientador(es)
Resumo(s)
Variants in the 5-lipoxygenase-activating protein (ALOX5AP) and phosphodiesterase 4D (PDE4D) genes have first been associated with ischemic stroke (IS) through whole-genome linkage screens. However, association studies obtained conflicting results. We aimed to investigate the contribution of selected single nucleotide polymorphisms (SNPs) in these genes for the first time in a large Iberian population.
Descrição
Palavras-chave
ALOX5AP Single nucleotide polymorphism Meta-analysis Stroke Genetics PDE4D Doenças Cardio e Cérebro-vasculares
Contexto Educativo
Citação
Cerebrovasc Dis. 2010;29(6):528-37. Epub 2010 Mar 30.