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Specific serology for emerging human coronaviruses by protein microarray

2013-04-04Journal article Open access
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dc.contributor.authorReusken, C.
dc.contributor.authorMou, H.
dc.contributor.authorGodeke, G. J.
dc.contributor.authorHoek, L.
dc.contributor.authorMeyer, B.
dc.contributor.authorMüller, M. A.
dc.contributor.authorHaagmans, B.
dc.contributor.authorSousa, R.
dc.contributor.authorShuurman, N.
dc.contributor.authorRottier, P.
dc.contributor.authorOsterhaus, A.
dc.contributor.authorDrosten, C.
dc.contributor.authorBosch, B. J.
dc.contributor.authorKoopmans, M.
dc.date.accessioned2016-10-06T13:58:07Z
dc.date.available2016-10-06T13:58:07Z
dc.date.issued2013-04-04
dc.description.abstractWe present a serological assay for the specific detection of IgM and IgG antibodies against the emerging human coronavirus hCoV-EMC and the SARS-CoV based on protein microarray technology. The assay uses the S1 receptor-binding subunit of the spike protein of hCoV-EMC and SARS-CoV as antigens. The assay has been validated extensively using putative cross-reacting sera of patient cohorts exposed to the four common hCoVs and sera from convalescent patients infected with hCoV-EMC or SARS-CoV.pt_PT
dc.description.sponsorshipRdS was funded by the European Public Health Microbiology Training Program (EUPHEM), ECDC, Stockholm. LvdH, BH and AO were funded by the European Union FP7 project EMPERIE (contract number 223498).pt_PT
dc.identifier.citationEuro Surveill. 2013 Apr 4;18(14):20441pt_PT
dc.identifier.doi10.2807/1560-7917.ES2015.20.4.21023pt_PT
dc.identifier.issn1560-7917
dc.identifier.urihttp://hdl.handle.net/10400.18/4034
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherEuropean Centre for Disease Prevention and Controlpt_PT
dc.relation.publisherversionhttp://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20441pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectEmerging Human Coronavirusespt_PT
dc.subjectProtein Microarraypt_PT
dc.subjectSpecific Serologypt_PT
dc.subjectInfecções Sistémicas e Zoonosespt_PT
dc.titleSpecific serology for emerging human coronaviruses by protein microarraypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPage20441pt_PT
oaire.citation.titleEurosurveillancept_PT
oaire.citation.volume18(14)pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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