Specific serology for emerging human coronaviruses by protein microarray

We present a serological assay for the specific detection of IgM and IgG antibodies against the emerging human coronavirus hCoV-EMC and the SARS-CoV based on protein microarray technology. The assay uses the S1 receptor-binding subunit of the spike protein of hCoV-EMC and SARS-CoV as antigens. The assay has been validated extensively using putative cross-reacting sera of patient cohorts exposed to the four common hCoVs and sera from convalescent patients infected with hCoV-EMC or SARS-CoV.

Palavras-chave

Emerging Human Coronaviruses Protein Microarray Specific Serology Infecções Sistémicas e Zoonoses

URI

http://hdl.handle.net/10400.18/4034

Citação

Euro Surveill. 2013 Apr 4;18(14):20441

Editora

European Centre for Disease Prevention and Control

DOI

10.2807/1560-7917.ES2015.20.4.21023

Coleções

DDI - Artigos em revistas internacionais

Licença CC

cclicense-by-nc

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