Publication
Contribution to the hazard assessment of benchmark metallic nanomaterials through a set of in vitro genotoxicity assays
| dc.contributor.author | Vital, Nádia | |
| dc.contributor.author | El Yamani, Naouale | |
| dc.contributor.author | Pinhão, Mariana | |
| dc.contributor.author | Rúden-Pra, Elise | |
| dc.contributor.author | Louro, Henriqueta | |
| dc.contributor.author | Dušinská, Maria | |
| dc.contributor.author | Silva, Maria João | |
| dc.date.accessioned | 2019-02-27T11:14:22Z | |
| dc.date.available | 2019-02-27T11:14:22Z | |
| dc.date.issued | 2018-03-20 | |
| dc.description.abstract | Metallic nanomaterials are among the most commonly applied manufactured nanomaterials (NM). Regardless of the considerable efforts to assess their safety, the presently available data do not allow for general and consistent conclusions. Moreover, the validity of the classical in vitro testing systems for NMs hazard assessment has been questioned and needs confirmation. In the present study, the toxicity of three benchmark metallic NMs, including two insoluble NMs - titanium (NM-100) and cerium (NM-212) dioxides - and soluble silver nanorods/wires (NM-302) was investigated. A panel of in vitro genotoxicity tests that analyze different endpoints was applied and the physico-chemical properties of each NM were considered. | pt_PT |
| dc.description.sponsorship | EC FP7 NANoREG project (NMP4-LA-2013-310584); FCT-Portugal (UID/BIM/00009/2013); QualityNano project (INFRA-2010-262163, NILU-TAF-410 and NILU-TAF-403) | pt_PT |
| dc.description.version | N/A | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.18/5962 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.relation | A common European approach to the regulatory testing of nanomaterials | |
| dc.relation | A pan-European infrastructure for quality in nanomaterials safety testing | |
| dc.subject | Metallic Nanomaterials | pt_PT |
| dc.subject | Genotoxicity Tests | pt_PT |
| dc.subject | Chinese Hamster Lung (V79) Cells | pt_PT |
| dc.subject | Genotoxicidade Ambiental | pt_PT |
| dc.title | Contribution to the hazard assessment of benchmark metallic nanomaterials through a set of in vitro genotoxicity assays | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | A common European approach to the regulatory testing of nanomaterials | |
| oaire.awardTitle | A pan-European infrastructure for quality in nanomaterials safety testing | |
| oaire.awardURI | info:eu-repo/grantAgreement/EC/FP7/310584/EU | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/5876/UID%2FBIM%2F00009%2F2013/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/EC/FP7/262163/EU | |
| oaire.citation.conferencePlace | Potsdam, Germany | pt_PT |
| oaire.citation.title | 46th EEMGS (European Environmental Mutagenesis and Genomics Society)/30th GUM (Gesellschaft für Umwelt-Mutationsforschung) meeting, 18-21 Mars 2018 | pt_PT |
| oaire.fundingStream | FP7 | |
| oaire.fundingStream | 5876 | |
| oaire.fundingStream | FP7 | |
| person.familyName | Louro | |
| person.givenName | Henriqueta | |
| person.identifier | 157627 | |
| person.identifier.ciencia-id | 721D-2BB1-7DB1 | |
| person.identifier.orcid | 0000-0001-9744-7332 | |
| person.identifier.scopus-author-id | 6507971479 | |
| project.funder.identifier | http://doi.org/10.13039/501100008530 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100008530 | |
| project.funder.name | European Commission | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | European Commission | |
| rcaap.rights | restrictedAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
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