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The Role of Health Preconditions on COVID-19 Deaths in Portugal: Evidence from Surveillance Data of the First 20293 Infection Cases

2020-07-24Journal article Open access
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dc.contributor.authorNogueira, Paulo Jorge
dc.contributor.authorde Araújo Nobre, Miguel
dc.contributor.authorCosta, Andreia
dc.contributor.authorRibeiro, Ruy M.
dc.contributor.authorFurtado, Cristina
dc.contributor.authorBacelar Nicolau, Leonor
dc.contributor.authorCamarinha, Catarina
dc.contributor.authorLuís, Márcia
dc.contributor.authorAbrantes, Ricardo
dc.contributor.authorVaz Carneiro, António
dc.date.accessioned2021-04-01T14:33:24Z
dc.date.available2021-04-01T14:33:24Z
dc.date.issued2020-07-24
dc.descriptionReply to Comment on Nogueira, P.J., et al. "The Role of Health Preconditions on COVID-19 Deaths in Portugal: Evidence from Surveillance Data of the First 20293 Infection Cases". J. Clin. Med. 2020, 9, 2368.Nogueira PJ, de Araújo Nobre M, Costa A, Ribeiro RM, Furtado C, Bacelar Nicolau L, Camarinha C, Luís M, Abrantes R, Carneiro AV.J Clin Med. 2020 Oct 27;9(11):3449. doi: 10.3390/jcm9113449.PMID: 33121184pt_PT
dc.description.abstractBackground: It is essential to study the effect of potential co-factors on the risk of death in patients infected by COVID-19. The identification of risk factors is important to allow more efficient public health and health services strategic interventions with a significant impact on deaths by COVID-19. This study aimed to identify factors associated with COVID-19 deaths in Portugal. Methods: A national dataset with the first 20,293 patients infected with COVID-19 between 1 January and 21 April 2020 was analyzed. The primary outcome measure was mortality by COVID-19, measured (registered and confirmed) by Medical Doctors serving as health delegates on the daily death registry. A logistic regression model using a generalized linear model was used for estimating Odds Ratio (OR) with 95% confidence intervals (95% CI) for each potential risk indicator. Results: A total of 502 infected patients died of COVID-19. The risk factors for increased odds of death by COVID-19 were: sex (male: OR = 1.47, ref = female), age ((56-60) years, OR = 6.01; (61-65) years, OR = 10.5; (66-70) years, OR = 20.4; (71-75) years, OR = 34; (76-80) years, OR = 50.9; (81-85) years, OR = 70.7; (86-90) years, OR = 83.2; (91-95) years, OR = 91.8; (96-104) years, OR = 140.2, ref = (0-55)), Cardiac disease (OR = 2.86), Kidney disorder (OR = 2.95), and Neuromuscular disorder (OR = 1.58), while condition (None (absence of precondition); OR = 0.49) was associated with a reduced chance of dying after adjusting for other variables of interest. Conclusions: Besides age and sex, preconditions justify the risk difference in mortality by COVID-19.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Clin Med. 2020 Jul 24;9(8):2368. doi: 10.3390/jcm9082368pt_PT
dc.identifier.doi10.3390/jcm9082368pt_PT
dc.identifier.issn2077-0383
dc.identifier.urihttp://hdl.handle.net/10400.18/7623
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2077-0383/9/8/2368pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCOVID-19pt_PT
dc.subjectArea Under the Curvept_PT
dc.subjectCancerpt_PT
dc.subjectCardiovascularpt_PT
dc.subjectDemographicspt_PT
dc.subjectDiabetespt_PT
dc.subjectEpidemiologypt_PT
dc.subjectLogistic Regressionpt_PT
dc.subjectMortalitypt_PT
dc.subjectSystemic Conditionpt_PT
dc.subjectInfecções Respiratóriaspt_PT
dc.titleThe Role of Health Preconditions on COVID-19 Deaths in Portugal: Evidence from Surveillance Data of the First 20293 Infection Casespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue8pt_PT
oaire.citation.startPage2368pt_PT
oaire.citation.titleJournal of Clinical Medicinept_PT
oaire.citation.volume9pt_PT
rcaap.embargofctAcesso de acordo com política editorial da revista.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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