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Congenital Anomalies and Cerebral Palsy: Data from the Portuguese Cerebral Palsy Surveillance Program

2025-06Documento de conferência Acesso aberto
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datacite.subject.fosCiências Naturais
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorCadete, Ana
dc.contributor.authorFolha, Teresa
dc.contributor.authorBraz, Paula
dc.contributor.authorCalado, Eulália
dc.contributor.authorAlvarelhão, Joaquim
dc.contributor.authorVirella, Daniel
dc.date.accessioned2026-03-03T12:23:39Z
dc.date.available2026-03-03T12:23:39Z
dc.date.issued2025-06
dc.description.abstractBackground and Objectives: Attention was recently drawn to the association of congenital anomalies (CA) with severity and complexity of cerebral palsy (CP). Evidence of this association is presented. Participants-Methods: The Portuguese National Surveillance of Cerebral Palsy (PNSCP) registers data of 5-to-8-year-old children with CP, born since 2001. The PNSCP follows the Surveillance of Cerebral Palsy in Europe (SCPE) common database protocol. Data were cross-referenced with the Portuguese National Registry of Congenital Anomalies. Children born between 2001-2015, notified until September 2024, were analyzed. CA were characterized according to ICD-10, following the EUROCAT criteria. Associations between the clinical forms of CP, complexity indicators and the presence of CA were explored. Results: Of 2251 registered children, 603 (27%; 95%CI 24.9-28.6) had at least one CA recorded; 228 children had multiple CA (10%; 95%CI 8.9-11.4). CA of the nervous system Q00-Q07 (CANS) are the most frequent (16%; 95%CI 14.9-18.0), followed by CA of the circulatory system Q20-Q28 (CACS) (4.9%; 95%CI 4.1-59). The odds of having at least one indicator of CP complexity increases by 2.6 times when having a CA (OR 2.6; 95%CI 2.01-3.48); slightly higher if a CANS exists (2.9; 95%CI 2.06-4,21), and slightly lower if a CACS exists (1.6; 95%CI 0.98-2.83). Conclusion: The prevalence of CA in children with CP is much higher than in the general population and increases the odds for greater severity and/or complexity of CP. The odds seems to be higher in the presence of CANS. This should be considered when assessing the prognosis and planning intervention.eng
dc.identifier.urihttp://hdl.handle.net/10400.18/11031
dc.language.isoeng
dc.peerreviewedyes
dc.rights.uriN/A
dc.subjectCerebral Palsy
dc.subjectCongenital Anomalies
dc.subjectPNVPC
dc.subjectRENAC
dc.subjectDeterminantes da Saúde e da Doença
dc.subjectPortugal
dc.titleCongenital Anomalies and Cerebral Palsy: Data from the Portuguese Cerebral Palsy Surveillance Programeng
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferenceDate2025-06
oaire.citation.conferencePlaceHeidelberg, Germany
oaire.citation.title37th European Academy of Childhood-onset Disability Annual Congress (EACD/IAACD), 24-28 June 2025
oaire.versionhttp://purl.org/coar/version/c_b1a7d7d4d402bcce

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