A carregar...
Publicação
Predominance of KPC-3 in a Survey for Carbapenemase-Producing Enterobacteriaceae in Portugal
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 173.96 KB | Adobe PDF |
Orientador(es)
Resumo(s)
Among the 2,105 Enterobacteriaceae tested in a survey done in Portugal, 165 were nonsusceptible to carbapenems, from which 35 (26 Klebsiella pneumoniae, 3 Escherichia coli, 2 Enterobacter aerogenes, and 3 Enterobacter cloacae isolates and 1 Klebsiella oxytoca isolate) were confirmed to be carbapenemase producers by the presence of 30 Tn4401d-blaKPC-3, 4 intI3-blaGES-5, and one intI1-blaVIM-2 gene, alone or in combination with other bla genes. The dissemination of blaKPC-3 gene carried by an IncF plasmid suggests lateral gene transfer as a major mechanism of dissemination.
Descrição
Free PMC Article: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432220/
Palavras-chave
Resistência aos Antibióticos Carbapenemases KPC-3 Portugal Enterobacteriaceae
Contexto Educativo
Citação
Antimicrob Agents Chemother. 2015;59(6):3588-92. doi: 10.1128/AAC.05065-14. Epub 2015 Mar 16.
Editora
American Society for Microbiology