Occupational secondhand smoke effect on nasal epithelial proteoma

Pacheco, Solange; Vaz, Fatima; Torres, Vukosava; Penque, Deborah; Simões, Tania; James, Peter

http://hdl.handle.net/10400.18/6839

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Abstract(s)

The tobacco is one of the biggest public health threats, smoking kills more than 7 million people/year worldwide and more than 890,000 are deaths resulting from exposure to Secondhand Smoke (SHS). In adults, SHS is associated to cardiovascular and respiratory diseases, including coronary heart disease and lung cancer, through pathological and molecular mechanisms not yet understood. In this study, we aimed to investigate the SHS effects on nasal epithelial proteome in exposed workers.