Antibiotic resistance: where are we and where are we going?

Manageiro, Vera

http://hdl.handle.net/10400.18/4486

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Authors

Manageiro, Vera

Abstract(s)

Antibiotic resistance is an emerging problem, becoming a serious threat to global public health. Indeed, we are seeing across Europe, namely in Portugal, an increasing number of patients with multidrug-resistant (MDR), extensively-drug resistant (XDR) and pandrug-resistant (PDR) infections, meaning there is no effective treatment available. New resistance mechanisms are disseminating worldwide, and the situation is aggravated by a low investment in this area, and specifically a substantial decline in the research and development of antibacterial agents, among others. Hence, very few new antibacterial classes are brought to market when older classes lose their efficacy. Antibiotic resistance constitutes a global health priority with severe consequences to humans, animals and to the environment, and should be tackled on all fronts in view to the actual concept of “One World - One Medicine - One Health”.