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Gaucher Disease and iPSCs: what does the future hold?
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Resumo(s)
Introduction: Currently we are working with induced
pluripotent stem cells (iPSCs) in order to
generate cells with the same genetic
background as the donor patients and further
differentiate them in cell types of interest for
the study of specific diseases. We are
manipulating human skin fibroblasts and have
included multiple checkpoints along the
procedures to avoid potential pitfalls.
Descrição
Palavras-chave
Gaucher Disease iPSCs Cell Models Human Genetics Doenças Genéticas