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Protocol for a systematic review and meta-analysis of human exposure to pesticide residues in honey and other bees’ products

2020-07Artigo científico Acesso aberto
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dc.contributor.authorSgargi, Daria
dc.contributor.authorAdam, Balazs
dc.contributor.authorBudnik, Lygia T.
dc.contributor.authorDinelli, Giovanni
dc.contributor.authorMoldovan, Horatiu Remus
dc.contributor.authorPerry, Melissa J.
dc.contributor.authorScheepers, Paul TJ.
dc.contributor.authorSchlünssen, Vivi
dc.contributor.authorTeixeira, João Paulo
dc.contributor.authorMandrioli, Daniele
dc.contributor.authorBelpoggi, Fiorella
dc.date.accessioned2021-03-04T14:56:25Z
dc.date.available2021-03-04T14:56:25Z
dc.date.issued2020-07
dc.descriptionMeta-Analysispt_PT
dc.description.abstractBackground: The presence of pesticides in honey and related products is an increasing concern for consumers and producers, although there is lack of data on the current burden of exposure of the general human population through these products. We present a protocol for a systematic review and meta-analysis of contamination to insecticides, herbicides and fungicides of products from honeybees, and an estimation of how much the consumption of these products contributes to the ADI (Acceptable Daily Intake) of selected substances. Objectives: We aim to systematically review and meta-analyse studies on the contamination to plant protection products in honey, royal jelly, beeswax and propolis, applying the Navigation Guide and WHO-ILO systematic review methodology as an organizing framework. Data sources: We will search electronic academic databases for potentially relevant records from PubMed, TOXNET and EMBASE. We will include quantitative studies analysing the contamination from insecticides, herbicides and fungicides in honey, propolis, royal jelly and beeswax. In particular, we will evaluate the presence of the following substances and classes of pesticides: Glyphosate, Chlorpyrifos, pyrethroid and neonicotinoid pesticides, fungicides and acaricides. Study appraisal and synthesis methods: At least two authors will independently screen titles and abstracts at a first stage of review, and full texts at a second stage, of potentially eligible records against the eligibility criteria; data extraction of included studies will then be performed by at least two authors, in blind. At least two authors will assess risk of bias and the quality of evidence, using the most suited tools currently available. The data on prevalence of contaminated samples and concentration of pesticides in the products will be combined using meta-analysis: when more than three studies reporting the necessary measures to fit the models are available, meta-analysis will be performed separately by product and by exposure; otherwise, weighted descriptive analysis will be performed. We will report the results using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA).pt_PT
dc.description.abstractHighlights: The presence of pesticides in honey and related products is an increasing concern for consumers and producers; We present a protocol for a systematic review of human exposure to pesticide residues in honey and other bees’ products; We will estimate of how much the consumption of these products contributes to the ADI of selected substances.
dc.description.sponsorshipThe project is funded by the EU-COST (under Grant no, CA 15129).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationEnviron Res. 2020 Jul;186:109470. doi: 10.1016/j.envres.2020.109470. Epub 2020 Apr 3.pt_PT
dc.identifier.doi10.1016/j.envres.2020.109470pt_PT
dc.identifier.issn0013-9351
dc.identifier.urihttp://hdl.handle.net/10400.18/7311
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevier/ Academic Presspt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0013935120303637?via%3Dihubpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAnimalspt_PT
dc.subjectBeespt_PT
dc.subjectHumanspt_PT
dc.subjectWorld Health Organizationpt_PT
dc.subjectHoneypt_PT
dc.subjectInsecticidespt_PT
dc.subjectOccupational Diseasespt_PT
dc.subjectOccupational Exposurept_PT
dc.subjectPesticide Residuespt_PT
dc.subjectAr e Saúde Ocupacionalpt_PT
dc.titleProtocol for a systematic review and meta-analysis of human exposure to pesticide residues in honey and other bees’ productspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPage109470pt_PT
oaire.citation.titleEnvironmental Researchpt_PT
oaire.citation.volume186pt_PT
rcaap.embargofctAcesso de acordo com política editorial da revista.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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