Repository logo
 
Publication

Analytical performance of 17 general chemistry analytes across countries and across manufacturers in the INPUtS project of EQA organizers in Italy, the Netherlands, Portugal, United Kingdom and Spain

2017-02Journal article Open access
Simple item page
dc.contributor.authorWeykamp, Cas
dc.contributor.authorSecchiero, Sandra
dc.contributor.authorPlebani, Mario
dc.contributor.authorThelen, Marc
dc.contributor.authorCobbaert, Christa
dc.contributor.authorThomas, Annette
dc.contributor.authorJassam, Nuthar
dc.contributor.authorBarth, Julian H.
dc.contributor.authorPerich, Carmen
dc.contributor.authorRicós, Carmen
dc.contributor.authorFaria, Ana Paula
dc.date.accessioned2017-02-13T15:20:16Z
dc.date.available2017-02-13T15:20:16Z
dc.date.issued2017-02
dc.description.abstractBACKGROUND: Optimum patient care in relation to laboratory medicine is achieved when results of laboratory tests are equivalent, irrespective of the analytical platform used or the country where the laboratory is located. Standardization and harmonization minimize differences and the success of efforts to achieve this can be monitored with international category 1 external quality assessment (EQA) programs. METHODS: An EQA project with commutable samples, targeted with reference measurement procedures (RMPs) was organized by EQA institutes in Italy, the Netherlands, Portugal, UK, and Spain. Results of 17 general chemistry analytes were evaluated across countries and across manufacturers according to performance specifications derived from biological variation (BV). RESULTS: For K, uric acid, glucose, cholesterol and high-density density (HDL) cholesterol, the minimum performance specification was met in all countries and by all manufacturers. For Na, Cl, and Ca, the minimum performance specifications were met by none of the countries and manufacturers. For enzymes, the situation was complicated, as standardization of results of enzymes toward RMPs was still not achieved in 20% of the laboratories and questionable in the remaining 80%. CONCLUSIONS: The overall performance of the measurement of 17 general chemistry analytes in European medical laboratories met the minimum performance specifications. In this general picture, there were no significant differences per country and no significant differences per manufacturer. There were major differences between the analytes. There were six analytes for which the minimum quality specifications were not met and manufacturers should improve their performance for these analytes. Standardization of results of enzymes requires ongoing efforts.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationClin Chem Lab Med. 2017 Feb 1;55(2):203-211. doi: 10.1515/cclm-2016-0220pt_PT
dc.identifier.doi10.1515/cclm-2016-0220pt_PT
dc.identifier.issn1434-6621
dc.identifier.urihttp://hdl.handle.net/10400.18/4150
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherDe Gruyter/ European Federation of Clinical Chemistry and Laboratory Medicine and International Federation of Clinical Chemistry and Laboratory Medicinept_PT
dc.relation.publisherversionhttps://www.degruyter.com/view/j/cclm.2017.55.issue-2/cclm-2016-0220/cclm-2016-0220.xmlpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectCommutabilitypt_PT
dc.subjectExternal Quality Assessmentpt_PT
dc.subjectGeneral Chemistrypt_PT
dc.subjectReference Measurement Procedurespt_PT
dc.subjectTotal Errorpt_PT
dc.subjectPNAEQpt_PT
dc.subjectPrograma Nacional de Avaliação Externa da Qualidadept_PT
dc.subjectAEQpt_PT
dc.subjectAvaliação Externa da Qualidadept_PT
dc.titleAnalytical performance of 17 general chemistry analytes across countries and across manufacturers in the INPUtS project of EQA organizers in Italy, the Netherlands, Portugal, United Kingdom and Spainpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage211pt_PT
oaire.citation.startPage203pt_PT
oaire.citation.titleClinical Chemistry and Laboratory Medicinept_PT
oaire.citation.volume55(2)pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
CCLM_Analytical performance of 17 general chemistry analytes across countries and across manufacturers.pdf
Size:
552.17 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

DEP - Artigos em revistas internacionais