Publication
Estrogen metabolites for the diagnosis of schistosomiasis associated urinary bladder cancer
| dc.contributor.author | Botelho, M.C. | |
| dc.contributor.author | Alves, H. | |
| dc.contributor.author | Richter, J. | |
| dc.date.accessioned | 2016-05-25T12:22:40Z | |
| dc.date.available | 2016-05-25T12:22:40Z | |
| dc.date.issued | 2016-02-26 | |
| dc.description | Letter to the Editor | pt_PT |
| dc.description.abstract | In a recent issue of Cancer Letters Gouveia and colleagues [1] studied a series of 40 Angolan patients diagnosed with Urogenital Schistosomiasis (UGS). They reported that 45% of them presented UGS-associated Squamous Cell Carcinoma (SCC) and/or urothelial cell carcinoma [1]. In addition these authors performed Liquid Chromatography-Mass Spectrometry and this analysis revealed numerous estrogens like metabolites. These schistosome infection-associated metabolites included Catechol Estrogen Quinones (CEQ) and CEQ-DNA-adducts, two of which had been identified previously in S. haematobium [1-3]. They conclude suggesting that these metabolites can be expected to provide deeper insights into the carcinogenesis UGS-induced bladder cancer, and as biomarkers for diagnosis and/or prognosis of this neglected tropical disease-linked cancer. (...) | pt_PT |
| dc.identifier.citation | SM Trop Med J. 2016;1(1). pii: 1004. Epub 2016 Feb 26. | pt_PT |
| dc.identifier.issn | 2055-0936 | |
| dc.identifier.uri | http://hdl.handle.net/10400.18/3824 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | SM Group | pt_PT |
| dc.relation.publisherversion | http://smjournals.com/tropical-medicine/download.php?file=fulltext/smtmj-v1-1004.pdf | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | pt_PT |
| dc.subject | Urogenital Schistosomiasis | pt_PT |
| dc.subject | Cancer | pt_PT |
| dc.subject | Bladder Cancer | pt_PT |
| dc.title | Estrogen metabolites for the diagnosis of schistosomiasis associated urinary bladder cancer | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 2 | pt_PT |
| oaire.citation.startPage | 1 | pt_PT |
| oaire.citation.title | SM Tropical Medicine Journal | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |