Publication
Insights into the role of the physicochemical properties in the toxicity of SiO2 nanoparticles in rat alveolar epithelial RLE-6TN cells
| dc.contributor.author | Brandão, M.F.P. | |
| dc.contributor.author | Bessa, M.J. | |
| dc.contributor.author | Costa, C. | |
| dc.contributor.author | Fraga, S. | |
| dc.contributor.author | Haase, A. | |
| dc.contributor.author | Teixeira, J.P. | |
| dc.date.accessioned | 2019-03-06T16:37:39Z | |
| dc.date.available | 2019-03-06T16:37:39Z | |
| dc.date.issued | 2018-09 | |
| dc.description | Poster abstract publicado em:Toxicology Letters. 2018;295(Suppl.1):S212-S213. doi: 10.1016/j.toxlet.2018.06.921: Disponível em: https://www.sciencedirect.com/science/article/pii/S0378427418311603 | pt_PT |
| dc.description.abstract | Silica nanoparticles (SiO2 NPs) are easily produced in different sizes and surface modifications enabling their use in several industrial and biomedical applications, which increases the risk of human exposure to these nanoparticles. Because the toxicological profile of nanoparticles is dependent upon their physicochemical properties, the aim of this study was to investigate the influence of the physicochemical properties (size, surface capping and hydrophilicity/hydrophobicity) in the cyto- and genotoxicity of SiO2 NPs in rat alveolar epithelial cells (RLE-6TN), a primary target during inhalation exposure. | pt_PT |
| dc.description.sponsorship | This work is supported by Fundação para a Ciência e a Tecnologia through European project NanoToxClass (ERA-SIINN/0001/2013) and under the grants SFRH/BD/101060/2014, SFRH/BPD/96196/2013 and SFRH/BD/120646/2016. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.18/6079 | |
| dc.language.iso | eng | pt_PT |
| dc.relation | Establishing nanomaterial grouping/ classification strategies according to toxicity and biological effects for supporting risk assessment | |
| dc.subject | Silica Nanoparticles | pt_PT |
| dc.subject | SiO2 NPs | pt_PT |
| dc.subject | Nanoparticles | pt_PT |
| dc.subject | Genotoxicidade Ambiental | pt_PT |
| dc.title | Insights into the role of the physicochemical properties in the toxicity of SiO2 nanoparticles in rat alveolar epithelial RLE-6TN cells | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Establishing nanomaterial grouping/ classification strategies according to toxicity and biological effects for supporting risk assessment | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/3599-PPCDT/ERA-SIINN%2F0001%2F2013/PT | |
| oaire.citation.conferencePlace | Brussels, Belgium | pt_PT |
| oaire.citation.title | 54th Congress of the European Societies of Toxicology (EUROTOX 2018), 2-5 September 2018 | pt_PT |
| oaire.fundingStream | 3599-PPCDT | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | embargoedAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
| relation.isProjectOfPublication | a118e28a-71df-4d9f-b18c-9d4e164baf22 | |
| relation.isProjectOfPublication.latestForDiscovery | a118e28a-71df-4d9f-b18c-9d4e164baf22 |