Loading...
Publication
O treino intensivo pode levar ao aumento de dano oxidativo no ADN em bailarinos profissionais?
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 1.62 MB | Adobe PDF |
Advisor(s)
Abstract(s)
A prática de exercício físico é imprescindível para a manutenção de um
estilo de vida saudável. No entanto, quando praticado acima de uma
determinada intensidade e duração, este pode levar à produção excessiva
de espécies reativas de oxigénio e consequentemente à indução
de stress oxidativo; este, por sua vez, pode desencadear alterações
em diversas estruturas biológicas. O objetivo deste estudo foi avaliar o
dano oxidativo no ADN em bailarinos da Companhia Nacional de Bailado
antes e depois da temporada de bailado (setembro a julho). A população
de estudo consistiu num total de 28 participantes: 14 bailarinos profissionais
e 14 indivíduos da população geral (grupo controlo). O dano primário
e o d ano o xidativo n o A DN f oram a valiados e m a mostras d e s angue
total através do teste do cometa. Os resultados obtidos revelam um
aumento significativo do dano oxidativo no ADN após a temporada de
bailado ( p<0.001; 1.1 ± 0.2 para 4.7 ± 0.7 ). Os níveis de dano oxidativo
no ADN avaliados antes do início da temporada de bailado não mostraram
diferenças significativas em relação ao grupo controlo ( p> 0.05;
1.1 ± 0.2 vs 2.2 ± 0.5, respetivamente). Os resultados deste estudo reforçam
a necessidade da implementação de medidas por forma a mitigar o
risco ocupacional afeto à prática de exercício físico intensivo nestes profissionais.
Despite the numerous health benefits of physical activity, some studies reported that increased intensity and duration may induce oxidative stress in several cellular components. The aim of this study was to evaluate the DNA oxidative damage among a group of professional dancers from the National Ballet Company of Portugal, before and after a ballet season (September to July). The study population consisted of a total of 28 subjects: 14 professional dancers and 14 control subjects from the general population. To quantify the DNA damage among ballet dancers, blood samples were taken before and after the dancing season. The technique used in the present study to investigate the primary DNA damage and the oxidative DNA damage was the comet assay. The levels of oxidative DNA damage in dancers were significantly increased after the ballet season (p<0.001; 1.1 ± 0.2 to 4.7 ± 0.7 ). Pre-season levels of oxidative DNA damage did not significantly differ from obtained in the general population (p>0.05; 1.1 ± 0.2 vs 2.2 ± 0.5, respectively). Results of the present biomonitoring study indicate the need for more effective measures to protect ballet dancers from potential occupational health risks related to regular intensive physical exercise.
Despite the numerous health benefits of physical activity, some studies reported that increased intensity and duration may induce oxidative stress in several cellular components. The aim of this study was to evaluate the DNA oxidative damage among a group of professional dancers from the National Ballet Company of Portugal, before and after a ballet season (September to July). The study population consisted of a total of 28 subjects: 14 professional dancers and 14 control subjects from the general population. To quantify the DNA damage among ballet dancers, blood samples were taken before and after the dancing season. The technique used in the present study to investigate the primary DNA damage and the oxidative DNA damage was the comet assay. The levels of oxidative DNA damage in dancers were significantly increased after the ballet season (p<0.001; 1.1 ± 0.2 to 4.7 ± 0.7 ). Pre-season levels of oxidative DNA damage did not significantly differ from obtained in the general population (p>0.05; 1.1 ± 0.2 vs 2.2 ± 0.5, respectively). Results of the present biomonitoring study indicate the need for more effective measures to protect ballet dancers from potential occupational health risks related to regular intensive physical exercise.
Description
Keywords
ADN Bailarinos Dano Oxidativo Treino Intensivo Avaliação do Risco Saúde Ocupacional
Pedagogical Context
Citation
Boletim Epidemiológico Observações. 2022;11(Supl 14):60-64
Publisher
Instituto Nacional de Saúde Doutor Ricardo Jorge, IP