Accuracy of prenatal culture in predicting intrapartum group B streptococcus colonization status

Objective: To evaluate the positive predictive value (PPV) of group B Streptococcus (GBS) cultures at 35–37 weeks of gestation relative to GBS colonization status at delivery. Methods: Rectovaginal swabs from 221 women at labor in four Lisbon hospitals were collected for GBS screening according to the CDC guidelines. Results: The PPV was 24.4%. IAP was administered to 100% of prenatally GBS positive women. There was no case of early onset GBS disease (EOD). Conclusions: Poor accuracy of prenatal cultures in identifying true candidates for IAP highlights the need for Portuguese clinical and laboratory guidelines to prevent EOD and antibiotic overtreatment of pregnant women.

Palavras-chave

Early Onset Disease Streptococcus agalactiae Intrapartum Antibiotic Prophylaxis Intrapartum Screening Infecções Sexualmente Transmissíveis

URI

http://hdl.handle.net/10400.18/2975

Citação

J Matern Fetal Neonatal Med. 2014 Apr;27(6):640-2. doi: 10.3109/14767058.2013.820700. Epub 2013 Aug 7

Editora

Informa Healthcare

DOI

10.3109/14767058.2013.820700

Coleções

DDI - Artigos em revistas internacionais

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