Publicação
Opinion on Ethylhexyl Methoxycinnamate (EHMC) (CAS No. 5466-77-3/83834-59-7, EC No. 226-775-7/629-661-9)
| dc.contributor.author | European Comission. Scientific Committee on Consumer Safety | |
| dc.date.accessioned | 2026-02-09T15:08:15Z | |
| dc.date.available | 2026-02-09T15:08:15Z | |
| dc.date.issued | 2025-06-26 | |
| dc.description | SCC (Scientific Committee on Consumer Safety), Opinion on Ethylhexyl Methoxycinnamate (EHMC) (CAS No. 5466-77-3/83834-59-7, EC No. 226-775-7/629-661-9), preliminary version of 25 October 2024, final version of 26 June 2025, SCCS/1671/24. | |
| dc.description | SCS External Experts: Benfenati, E; Cabaton, N (Rapporteur); Corsini, E; Koutsodimou, A; Louro, Maria Henriqueta; Ulter, W; von Goetz, N. | |
| dc.description | SCCS/1671/24 Final version: Opinion on Ethylhexyl Methoxycinnamate (EHMC) (CAS No. 5466-77-3/83834-59-7, EC No. 226-775-7/629-661-9 | |
| dc.description.abstract | The SCCS concludes the following: 1. In light of the data provided and taking under consideration the concerns related to potential endocrine disrupting properties of Ethylhexyl Methoxycinnamate, does the SCCS consider Ethylhexyl Methoxycinnamate safe when used as UV-Filter in cosmetic products up to a maximum concentration of 10%? The SCCS has noted that the available evidence shows that EHMC is an endocrineactive substance due to estrogenic activity and weak anti-androgenic activity both in vitro and in vivo. Having considered the data provided, and the concerns relating to potential endocrine disrupting properties of EHMC, the SCCS is of the opinion that EHMC is safe when used as a UV filter up to a maximum concentration of 10% in sunscreen lotion, face and hand cream, lipstick, sunscreen propellant spray and pump spray, when used separately or in combination. The SCCS is of the opinion that these products are also safe for children due to the high Margin of Safety, which precludes any difference between internal exposures in children that might be higher due to a different surface/body weight ratio than in adults. 2. Alternatively, what is according to the SCCS the maximum concentration considered safe for use of Ethylhexyl Methoxycinnamate in cosmetic products? 3. Does the SCCS have any further scientific concerns with regard to the use of Ethylhexyl Methoxycinnamate in cosmetic products? The SCCS mandate does not address environmental aspects. Therefore, this assessment did not cover the safety of EHMC for the environment. | eng |
| dc.identifier.uri | http://hdl.handle.net/10400.18/10864 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.publisher | European Commission. Health and Food Safety | |
| dc.relation.hasversion | https://health.ec.europa.eu/publications/sccs-opinion-ethylhexyl-methoxycinnamate-ehmc-cas-no-5466-77-383834-59-7-ec-no-226-775-7629-661-9_en | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Ethylhexyl Methoxycinnamate (EHMC)namate (OMC) | |
| dc.subject | Cosmetic Ingredients | |
| dc.subject | Safety Assessment | |
| dc.subject | Environmental Genotoxicity | |
| dc.subject | Octylmethoxycinnamate (OMC) | |
| dc.subject | Octinoxate | |
| dc.subject | Regulation 1223/2009 | |
| dc.subject | CAS No. 5466-77- 3/83834-59-7 | |
| dc.subject | EC No. 226-775-7/629-661-9 | |
| dc.subject | Ethylhexyl Methoxycinnamate (EHMC) | |
| dc.subject | Genotoxicidade Ambiental | |
| dc.title | Opinion on Ethylhexyl Methoxycinnamate (EHMC) (CAS No. 5466-77-3/83834-59-7, EC No. 226-775-7/629-661-9) | eng |
| dc.type | report | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 101 | |
| oaire.citation.startPage | 2 | |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 |