Genetic alterations of ALK in high-risk neuroblastoma patients: a SIOPEN study

http://hdl.handle.net/10400.18/5900

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Authors

Bellini, Angela

Bernard, Virginie

Ambros, Peter F.

de Preter, Katleen

Combaret, Valérie

Marques, Barbara

Morini, Martina

Abstract(s)

Background: In neuroblastoma (NB), the ALK receptor tyrosine kinase can be constitutively activated either through genomic amplification or activating point mutations. We studied ALK genetic alterations in high-risk NB patients to determine their frequency and prognostic impact.

Keywords

Neuroblastoma ALK Tumor Genomics Doenças Genéticas

URI

http://hdl.handle.net/10400.18/5900

Collections

DGH - Posters/abstracts em congressos internacionais

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