Repository logo
 
Publication

Patulin and ochratoxin A co-occurrence and their bioaccessibility in processed cereal-based foods: a contribution for Portuguese children risk assessment

2016-10Journal article Restricted access
Simple item page
dc.contributor.authorAssunção, Ricardo
dc.contributor.authorMartins, Carla
dc.contributor.authorDupond, D.
dc.contributor.authorAlvito, Paula
dc.date.accessioned2017-01-06T15:44:30Z
dc.date.available2020-08-05T00:30:11Z
dc.date.issued2016-10
dc.description.abstractPatulin (PAT) and ochratoxin A (OTA) are well known enteropathogenic mycotoxins that are present in several foodstuffs. Processed cereal-based foods are among the first solid foods eaten by children, a particularly vulnerable population group. There is a lack of knowledge related to the co-occurrence of PAT and OTA in food intended for children consumption and their potential interactions during the digestion process. The present study aims to evaluate, for the first time, the co-occurrence of PAT and OTA in processed cereal-based foods for children consumption, the bioaccessibility of these two mycotoxins, and the contribution of the bioaccessibility data for human health risk assessment. PAT and OTA incidence were 75% and 50%, respectively. These mycotoxins co-occurred in 40% of analysed samples. Bioaccessibility assays revealed mean values of 52% and 56% for PAT, alone and combined with OTA; and 100% and 106% for OTA, alone and combined with PAT. Considering the human health risk assessment, and taking into account the co-occurrence and the bioaccessibility results, this study indicates a tolerable exposure to these mycotoxins representing a low risk for Portuguese children. The present work reinforces the importance of a holistic approach for risk assessment which gathers data from occurrence, exposure and bioaccessibility.pt_PT
dc.description.sponsorshipThis research was supported by the project MYCOMIX (PTDC/DTP-FTO/0417/2012) and through CESAM (UID/AMB/50017/2013) both funded by the Fundação para a Ciência e Tecnologia, Portugal. The authors would like to thanks to COST action FA1005 INFOGEST for the support and training in standardised static in vitro digestion method and to Dr. Elsa Vasco for advice and support regarding children food consumption.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFood Chem Toxicol. 2016 Oct;96:205-14. doi: 10.1016/j.fct.2016.08.004. Epub 2016 Aug 4pt_PT
dc.identifier.doi10.1016/j.fct.2016.08.004pt_PT
dc.identifier.issn0278-6915
dc.identifier.urihttp://hdl.handle.net/10400.18/4118
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevier/Pergamonpt_PT
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0278691516302708pt_PT
dc.subjectSegurança Alimentarpt_PT
dc.subjectToxicologiapt_PT
dc.subjectAvaliação de Riscopt_PT
dc.subjectSaúde Humanapt_PT
dc.subjectRisk Assessmentpt_PT
dc.subjectBioaccessibilitypt_PT
dc.subjectMycotoxinspt_PT
dc.subjectStandardised in vitro digestionpt_PT
dc.subjectChildrenpt_PT
dc.titlePatulin and ochratoxin A co-occurrence and their bioaccessibility in processed cereal-based foods: a contribution for Portuguese children risk assessmentpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FDTP-FTO%2F0417%2F2012/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FAMB%2F50017%2F2013/PT
oaire.citation.endPage214pt_PT
oaire.citation.startPage205pt_PT
oaire.citation.titleFood and Chemical Toxicologypt_PT
oaire.citation.volume96pt_PT
oaire.fundingStream3599-PPCDT
oaire.fundingStream5876
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctPolítica de copyright e de auto-arquivo do editor.pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isProjectOfPublication7dee8a4a-7112-45ce-a8cb-8c552d7ae061
relation.isProjectOfPublication1d7db62a-6440-4ccb-a5cc-c3f76c8585b3
relation.isProjectOfPublication.latestForDiscovery1d7db62a-6440-4ccb-a5cc-c3f76c8585b3

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
2016_Assunção et al (PAT OTA Bioaccessibility).pdf
Size:
394.84 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

DAN - Artigos em revistas internacionais