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Deliverable 6: Characterisation of manufactured nanomaterials for their clastogenic/aneugenic effects or DNA damage potentials and correlation analysis. Final report.

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Abstract(s)

Objectives: To generate data from selected in vivo genotoxicity tests, and to assess the correlation between in vivo and in vitro results taking into account the kinetic results. Schedule: The WP6 lasted for 16 months from October 2011 until the end of the Joint Action (February 2013). Few months at the beginning were devoted to trainings and trials before performing the experiments on Manufactured Nanomaterials (MNs). Even though, some last results are not yet available and will be collected after the end of the Joint Action, especially on the micronucleus on colon as well as on histology.

Description

This document arises from the NANOGENOTOX Joint Action which has received funding from the European Union, in the framework of the Health Programme under Grant Agreement n°2009 21.
WP6: In vivo testing of nanomaterial genotoxicity
WP6 partners: INSA, IP: Maria João Silva; Ana Tavares, Henriqueta Louro, Nádia Vital

Keywords

Genotoxicidade Ambiental Nanomaterials In Vivo Genotoxicity lacZ Transgenic Mouse Genómica Funcional e Estrutural

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Nnanogenotox

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