Publication
Schistosoma mansoni infection impairs reproduction in mice
| dc.contributor.author | Botelho, M. | |
| dc.contributor.author | Lopes, G. | |
| dc.contributor.author | Gartner, F. | |
| dc.contributor.author | Alves, H. | |
| dc.contributor.author | Richter, J. | |
| dc.date.accessioned | 2017-02-13T16:33:26Z | |
| dc.date.available | 2017-02-13T16:33:26Z | |
| dc.date.issued | 2016-10 | |
| dc.description.abstract | AIM: To study the effect of S. mansoni infection in fertility using a mouse model. BACKGROUND: - Our group is listed in the Top 10 most publishing authors in the field of schistosomiasis as a cause of infertility; - Estrogen-like molecules produced by schistosomes haematobia and mansoni induce hormonal imbalances in infected persons; - These estrogenic metabolites down-regulate Estrogen Receptor in an in vitro model; - We have identified these estrogenic metabolites as catechol-estrogens (oxidative metabolites derived from estrogens); - These catechol-estrogens were found to be associated with infertility in women infected with S. haematobium. | pt_PT |
| dc.description.version | N/A | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.18/4156 | |
| dc.language.iso | eng | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | pt_PT |
| dc.subject | Schistosoma Mansoni | pt_PT |
| dc.subject | Infertility | pt_PT |
| dc.title | Schistosoma mansoni infection impairs reproduction in mice | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Bonn, Germany | pt_PT |
| oaire.citation.title | Annual Meeting of the German Society of Tropical Medicine (DTG), 7–8 October 2016 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |