Publication
High frequency of subclonal ALK mutations in high risk neuroblastoma patients. A SIOPEN study
| dc.contributor.author | Bellini, Angela | |
| dc.contributor.author | Bernard, Virginie | |
| dc.contributor.author | Lapouble, Eve | |
| dc.contributor.author | Clement, Nathalie | |
| dc.contributor.author | Pierron, Gaelle | |
| dc.contributor.author | Ambros, Inge M. | |
| dc.contributor.author | Preter, Katleen de | |
| dc.contributor.author | Van Roy, Nadine | |
| dc.contributor.author | Vicha, Ales | |
| dc.contributor.author | Combaret, Valérie | |
| dc.contributor.author | Betts, David | |
| dc.contributor.author | Jeison, Marta | |
| dc.contributor.author | Avigad, Smadar | |
| dc.contributor.author | Morini, Martina | |
| dc.contributor.author | Varesio, Luigi | |
| dc.contributor.author | Marques9, Barbara | |
| dc.contributor.author | Muhlethaler, Annick | |
| dc.contributor.author | Noguera, Rosa | |
| dc.contributor.author | Berbegall, Ana | |
| dc.contributor.author | Mora, Jaime Font de | |
| dc.contributor.author | Ambros, Peter F. | |
| dc.contributor.author | Ladenstein, Ruth | |
| dc.contributor.author | Valteau-Couanet, Dominique | |
| dc.contributor.author | Michon, Jean | |
| dc.contributor.author | Delattre, Olivier | |
| dc.contributor.author | Bown, Nick | |
| dc.contributor.author | Tweddle, Deborah | |
| dc.contributor.author | Schleiermache, Gudrun | |
| dc.date.accessioned | 2016-03-04T19:13:54Z | |
| dc.date.available | 2016-03-04T19:13:54Z | |
| dc.date.issued | 2015-11 | |
| dc.description.abstract | Introduction: In neuroblastoma (NB), activating ALK receptor tyrosine kinase point mutations are detected in 8–10% at diagnosis using conventional sequencing. To determine the potential occurrence and the prognostic impact of ALK mutations in a series of high risk NB patients we studied ALK variation frequencies using targeted deep sequencing in samples of patients enrolled in the SIOPEN HR-NBL01 study | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.18/3679 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.subject | Neuroblastoma | pt_PT |
| dc.subject | SIOPEN | pt_PT |
| dc.subject | ALK | pt_PT |
| dc.subject | High Risk | pt_PT |
| dc.subject | Doenças Genéticas | pt_PT |
| dc.title | High frequency of subclonal ALK mutations in high risk neuroblastoma patients. A SIOPEN study | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Newcastle, UK | pt_PT |
| oaire.citation.title | Annual General Meeting and 4th Neuroblastoma Research Symposium (SIOPEN), 24-27 November 2015 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |