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Functional compatibility of PB1 and antigenic proteins as a determinant of viral fitness and adaptation in the A(H1N1)pdm09

dc.contributor.authorGíria, Marta
dc.contributor.authorLouro, João
dc.contributor.authorRebelo de Andrade, Helena
dc.date.accessioned2017-03-14T14:28:53Z
dc.date.available2017-03-14T14:28:53Z
dc.date.issued2016-08
dc.description.abstractObjectives: To determine if the functional compatibility between PB1 and antigenic proteins is a molecular determinant of virus growth and antigen yield in PR8:A(H1N1)pdm09 reassortants; To evaluate the phenotypic expression of reverting mutations R386K, I517V and L298I, previously identified as putatively associated with an enhanced functional compatibility between PB1 and HA in the A(H1N1)pdm09pt_PT
dc.description.versionN/Apt_PT
dc.identifier.urihttp://hdl.handle.net/10400.18/4637
dc.language.isoengpt_PT
dc.subjectPB1pt_PT
dc.subjectAntigenic Proteinspt_PT
dc.subjectInfluenza Viruspt_PT
dc.subjectA(H1N1)pdm09pt_PT
dc.subjectInfluenzapt_PT
dc.subjectInfecções Respiratóriaspt_PT
dc.titleFunctional compatibility of PB1 and antigenic proteins as a determinant of viral fitness and adaptation in the A(H1N1)pdm09pt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceChicago, USApt_PT
oaire.citation.titleOptions IX for The Control of Influenza, 24-28 Aug 2016pt_PT
rcaap.rightsrestrictedAccesspt_PT
rcaap.typeconferenceObjectpt_PT

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