Publication
Functional compatibility of PB1 and antigenic proteins as a determinant of viral fitness and adaptation in the A(H1N1)pdm09
| dc.contributor.author | Gíria, Marta | |
| dc.contributor.author | Louro, João | |
| dc.contributor.author | Rebelo de Andrade, Helena | |
| dc.date.accessioned | 2017-03-14T14:28:53Z | |
| dc.date.available | 2017-03-14T14:28:53Z | |
| dc.date.issued | 2016-08 | |
| dc.description.abstract | Objectives: To determine if the functional compatibility between PB1 and antigenic proteins is a molecular determinant of virus growth and antigen yield in PR8:A(H1N1)pdm09 reassortants; To evaluate the phenotypic expression of reverting mutations R386K, I517V and L298I, previously identified as putatively associated with an enhanced functional compatibility between PB1 and HA in the A(H1N1)pdm09 | pt_PT |
| dc.description.version | N/A | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.18/4637 | |
| dc.language.iso | eng | pt_PT |
| dc.subject | PB1 | pt_PT |
| dc.subject | Antigenic Proteins | pt_PT |
| dc.subject | Influenza Virus | pt_PT |
| dc.subject | A(H1N1)pdm09 | pt_PT |
| dc.subject | Influenza | pt_PT |
| dc.subject | Infecções Respiratórias | pt_PT |
| dc.title | Functional compatibility of PB1 and antigenic proteins as a determinant of viral fitness and adaptation in the A(H1N1)pdm09 | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Chicago, USA | pt_PT |
| oaire.citation.title | Options IX for The Control of Influenza, 24-28 Aug 2016 | pt_PT |
| rcaap.rights | restrictedAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |